Pollen Food Allergy Syndrome in Japanese Children and Adolescents: Risk Factors and Pollen Sensitisation

Table 4

Multivariate logistic regression analysis for the development of PFAS.

	PFAS	No PFAS	Reference	OR	95% CI	value
N	123	477
Age, years	12 (4-18)	8 (3-18)	Per 1 year	1.12	1.06–1.19	<0.001
Male	75 (61.0%)	303 (63.5%)	vs. female	0.67	0.42–1.06	0.087
Female	48 (39.0%)	174 (36.5%)	vs. male	1.49	0.94–2.38	0.087
Allergic diagnosis
Food allergy^†	66 (53.7%)	301 (63.1%)	vs. negative	0.60	0.38–0.96	0.034
Atopic dermatitis	76 (61.8%)	247 (51.8%)	vs. negative	1.20	0.76–1.89	0.439
Bronchial asthma	32 (26.0%)	168 (35.2%)	vs. negative	0.63	0.38–1.03	0.064
Seasonal allergic rhinitis	121 (98.4%)	340 (71.3%)	vs. negative	6.93	1.59–30.34	0.010
Pollen-specific IgE-positive rate (%)
Alder	114 (92.7%)	257 (53.9%)	vs. negative	6.20	2.66–14.49	<0.001
Japanese cedar	123 (100%)	471 (98.7%)	vs. negative	—	—	—
Ragweed	100 (81.3%)	238 (49.9%)	vs. negative	1.20	0.62–2.33	0.585
Orchard grass	107 (87.0%)	273 (57.2%)	vs. negative	1.08	0.51–2.30	0.841

OR: odds ratio; 95% CI: 95% confidence interval. Subjects: all patients (). ^†Excluding PFAS.