Necrostatin-1 Alleviates Diffuse Pulmonary Haemorrhage by Preventing the Release of NETs via Inhibiting NE/GSDMD Activation in Murine Lupus

<div>Neutrophil extracellular traps (NETs) damage alveolar epithelial cells in a dose-dependent manner. (a) A549 cells were cultured with different concentrations of NETs, and the morphological changes were observed under an optical fibre microscope. Representative images of the A549 cells are shown. (b) The proliferation of A549 cells was further detected using an enzyme-plate analyser. 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Journal of Immunology Research

fig1

Figure 1

Figure 1: Necrostatin-1 Alleviates Diffuse Pulmonary Haemorrhage by Preventing the Release of NETs via Inhibiting NE/GSDMD Activation in Murine Lupus 

Figure 1 | Necrostatin-1 Alleviates Diffuse Pulmonary Haemorrhage by Preventing the Release of NETs via Inhibiting NE/GSDMD Activation in Murine Lupus 