Necrostatin-1 Alleviates Diffuse Pulmonary Haemorrhage by Preventing the Release of NETs via Inhibiting NE/GSDMD Activation in Murine Lupus

<div>Schematic illustration of Necrostatin-1 (Nec-1) ameliorating diffuse alveolar haemorrhage in systemic lupus erythematosus by inhibiting the activation of neutrophil elastase (NE)/N-GSDMD to prevent neutrophil extracellular trap (NET) release.</div>

Journal of Immunology Research

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Figure 6

Figure 6: Necrostatin-1 Alleviates Diffuse Pulmonary Haemorrhage by Preventing the Release of NETs via Inhibiting NE/GSDMD Activation in Murine Lupus 

Figure 6 | Necrostatin-1 Alleviates Diffuse Pulmonary Haemorrhage by Preventing the Release of NETs via Inhibiting NE/GSDMD Activation in Murine Lupus 