DJ-1: A Potential Biomarker Related to Prognosis, Chemoresistance, and Expression of Microenvironmental Chemokine in HR-Positive Breast Cancer
Table 1
Characteristics of HR+ patients between DJ-1 high and low groups in TCGA dataset.
Characteristics
Low expression group
High expression group
N
χ2
P
Age (years)
≤60
158
154
312
0.059
0.81
>60
138
140
278
AJCC stage
1
47
67
114
4.11
4.26 × 10−2
2–4
243
226
469
T stage
T1
80
87
167
0.48
0.49
T2–4
216
207
423
N stage
N0
131
138
269
1.57
0.46
N1–3
162
151
313
Not availablea
3
6
9
Pathological subtype
Infiltrating ductal carcinoma
188
201
389
4.89
8.67 × 10−2
Infiltrating lobular carcinoma
84
62
146
Other
24
32
56
Menopause statusb
Pre
77
59
136
3.63
0.30
Peri
8
10
18
Post
192
201
393
Not availablea
19
25
44
Race
Asian
9
17
26
18.84
2.94 × 10−4
Black or African-American
22
52
74
White
238
196
434
Not availablea
27
30
57
aData not available. bPre, <6 months since LMP AND no prior bilateral ovariectomy AND not on estrogen replacement, Peri: 6–12 months since last menstrual period; Post, prior bilateral ovariectomy OR >12 months since LMP with no prior hysterectomy. Bold values signify that .
