Research Article
Diagnostic Value of CD25, CD69, and CD134 on Tuberculosis-Specific Antigen-Stimulated CD4+ T Cells for Tuberculous Pleurisy
Table 1
Clinical and laboratory characteristics of study participants.
| | Variables | Cohort 1 | Cohort 2 | | ATB (n = 45) | LTBI (n = 40) | NTBb (n = 50) | HC (n = 42) | TP (n = 28) | NTP (n = 36) |
| | Age, years | 70.0
(51.0–86.0) | 70.5
(51.0–86.8) | 70.0
(50.3–89.0) | 59.5
(52.8–70.0) | 62.5
(53.5–68.0) | 63.5 ± 11.4 | | Gender, male (n, %) | 25 (55.6%) | 24 (60.0%) | 27 (54.0%) | 28 (66.7%) | 19 (67.9%) | 25 (69.4%) | | Radiological findingsa (n, %) | 8 (17.8%) | 4 (10.0%) | 0 | 0 | | | | Acid-fast bacilli smear positive (n, %) | 20 (44.4%) | 0 | 0 | 0 | 2 (7.1%) | 0 | | Xpert MTB/RIF positive (n, %) | 28(62.2%) | 0 | 0 | 0 | 7 (25.0%) | 0 | | Mtb culture positive (n, %) | 22 (48.9%) | 0 | 0 | 0 | 2 (7.1%) | 0 | | TB-IGRA positive (n, %) | 44 (97.8%) | 40(100.0%) | 0 | 0 | 24 (85.7%) | 8 (22.2%) | | ADA (U/L) | NA | NA | NA | NA | 44.6
(34.2–55.4) | 11.9
(7.6–21.0) |
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Note: ATB = active tuberculosis; LTBI = latent tuberculosis infection; NTB = nontuberculosis; HC = healthy control; TP = tuberculous pleurisy; NTP = nontuberculous pleurisy; Mtb = Mycobacterium tuberculosis; NA = not applicable. aLung shadow or pathological changes. bDisease type of NTB: chronic disease, 19 (38.0%); infectious diseases, 14 (28.0%); autoimmune diseases,12 (24.0%); tumors, 5 (10.0%).
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