Antieosinophil Antibodies Alone or in Combination with Antineutrophil Cytoplasmic Antibodies (ANCA) Detected in Different Autoimmune Conditions

Figure 4

Antibody titers at study inclusion and at the first follow-up as determined by ELISA against (a) eosinophil peroxidase (anti-EPX), (b) eosinophil cationic protein (anti-ECP), and (c) myeloperoxidase (anti-MPO). The antibody titers are expressed as arbitrary units at OD 450 nm normalized to a reference serum. E-group refers to sera from AEOSA+/ANCA− patient samples and D-group refers to AEOSA+/ANCA+ patient samples. The cutoff limit (indicated with dashed line) was set at +3 SD above the average signal in healthy controls.

(a)

(b)

(c)