The Expression of Semaphorin3E in Vagal Ganglion and Lung Tissue Is Related to Airway Hyperresponsiveness in Murine Asthma Model

Figure 2

OVA-induced asthma and EB mouse models showed similar airway inflammation but different airway hyperresponsiveness. (a) The number of coughs in the four groups of mice. (b) The airway reactivity of mice in four groups. (c) The total inflammatory cell counts in the BALF of mice for the four groups. (d) Eos% in BALF of mice in the four groups. (e) Differential cell counts in BALF. (f) The lung tissue pathological sections of the four mice groups were stained with HE. (Compared with NS group, : ; : , : ; compared with EB group, ^#: ; ^##: , ^###: ). Data were expressed as mean ± standard deviation (n = 6) (NS: nasal saline group, AS: asthma group, EB: eosinophilic bronchitis group, DXM: dexamethasone group, MCh: methacholine, Eos: eosinophil, Neu: Neutrophil, Mac: macrophage, and Lym: lymphocyte).

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