Broadly Reactive SARS-CoV-2-Specific T-Cell Response and Participation of Memory B and T Cells in Patients with Omicron COVID-19 Infection

Figure 2

Flow cytometry analysis of NK/NKT-like, B, memory B and IgG+ B cells, T-cell subsets among the study population. PBMCs from (a) total Omicron COVID-19 patients (n = 19); (b) vaccinated Omicron-infected patients (n = 15); (c) total mild COVID-19 (asymptomatic and mild symptomatic2020) (n = 45) patients; (d) uninfected controls (n = 18) were stained and acquired on a flow cytometer. Vertical scatter plots denote the comparisons of frequencies of immune cells and their subpopulation among different study groups: (a) NK cells; (b) NKT-like cells; (c) B cells; (d) memory B cells; (e) CD4⁺T-helper cells; (f) CD8⁺T-cytotoxic cells profile. Data are presented as percentage of immune cells out of lymphocytes. The dots represent individual values and bars represent mean + SD values (p-value < 0.05, p-value < 0.005, and p-value < 0.0001).

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