Small Extracellular Vesicles Secreted by iPSC-Derived MSCs Ameliorate Pulmonary Inflammation and Lung Injury Induced by Sepsis through Delivery of miR-125b-5p

<div>Characterization of induced pluripotent stem cell-derived mesenchymal stem cells and iMSC-sEV. (a) Flow cytometric analysis of the surface markers in iMSCs. (b) Morphology of iMSC-sEV observed by TEM (scale bar, 200 and 100 nm). (c) Particle size distribution of iMSC-sEV measured and identified through NanoSight tracking analysis. (d) Representative western blot assessment of iMSC-sEV and iMSCs lysates showing the presence of sEV markers, including CD9 and CD63.</div>

Journal of Immunology Research

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Figure 1: Small Extracellular Vesicles Secreted by iPSC-Derived MSCs Ameliorate Pulmonary Inflammation and Lung Injury Induced by Sepsis through Delivery of miR-125b-5p 

Figure 1 | Small Extracellular Vesicles Secreted by iPSC-Derived MSCs Ameliorate Pulmonary Inflammation and Lung Injury Induced by Sepsis through Delivery of miR-125b-5p 