Research Article

lncRNA HCG11 Promotes Colorectal Cancer Cell Malignant Behaviors via Sponging miR-26b-5p

Figure 1

lncRNA HCG11 knockdown subdues CRC cell growth and accelerates cell apoptosis. (a) HCG11 level in CRC cell lines (HCT15, HT-29, and LOVO) and human normal intestinal epithelial cells (NCM-460) was assessed using qRT-PCR. (b) qRT-PCR tested the interference efficiency of sh-HCG11 in HCT15 and HT-29. (c, d) The cell proliferation and colony capacities were evaluated with the assistance of EdU assay and colony formation assay. (e, f) Cell apoptosis was assessed via TUNEL assay and JC-1 assay. (g, h) Cell migration and invasion abilities were tested via transwell assay. and .
(a)
(b)
(c)
(d)
(e)
(f)
(g)
(h)