Clinical Significance of Different Profiles of anti-Ro Antibodies in Connective Tissue Diseases
Table 2
Comparison of laboratory data in patients with connective tissue diseases.
Parameters (, %)
Groups
values
Overall
All
Group A: Ro52 alone
Group B: Ro60 alone
Group C: Ro60 and Ro52
Group A vs. group B
Group A vs. group C
Group B vs. group C
IgG#>18 g/L
420 (34.9)
38 (25.2)
58 (22.3)
324 (40.9)
0.509
<0.0001
<0.0001
<0.0001
C3<0.8 g/L
404 (30.6)
27 (16.0)
78 (27.6)
299 (34.5)
0.005
<0.0001
0.031
<0.0001
C4<0.15 g/L
502 (38.1)
43 (25.4)
92 (32.5)
367 (42.3)
0.112
<0.0001
0.003
<0.0001
CRP>5 mg/L
418 (31.7)
70 (41.4)
102 (36.0)
246 (28.4)
0.255
0.001
0.015
0.001
ESR>20 mm/h
754 (57.2)
92 (54.4)
145 (51.2)
517 (59.6)
0.510
0.210
0.013
0.035
eGFR<60 mL/min/1.73m2
108 (8.2)
18 (10.7)
21 (7.4)
69 (8.0)
0.237
0.248
0.770
0.439
Albumin<30 g/L
218 (16.5)
25 (14.8)
42 (14.8)
151 (17.4)
0.989
0.406
0.314
0.485
RF
208 (20.1)
35 (28.2)
42 (17.7)
131 (19.4)
0.021
0.026
0.575
0.046
CRP: C-reaction protein; ESR: erythrocyte sedimentation rate. #116 patients without serum IgG result. A total of 282 patients did not have rheumatoid factor tested.
