Identification and Development of Synovial B-Cell-Related Genes Diagnostic Signature for Rheumatoid Arthritis

Figure 5

Diagnostic value of B-cell-related genes diagnostic signature. (a) Differential expression of the FAS, GPR183, and TFRC among total RA (RA), ACPA-positive (+)/-negative (−) RA, early/established RA patients, OA patients, and healthy control (HC). (b and c) Receiver-operating characteristic curves (ROC) analysis of FAS, GPR183, and TFRC for RA diagnosis in different comparison groups. (d–i) ROC analysis of the risk score established by FAS, GPR183, and TFRC in different comparison groups. (h) ROC analysis of the risk score established by FAS, GPR183, and TFRC in the GSE122616 dataset. (i) Differential expression of the FAS, GPR183, and TFRC between RA (n = 25) and OA (n = 25) patients in our clinical cohort. (j) ROC analysis of FAS, GPR183, and TFRC for RA diagnosis in our clinical cohort. , .

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