Disease Activity and Tendency to Relapse in ANCA-Associated Vasculitis Are Reflected in Neutrophil and Intermediate Monocyte Frequencies

Figure 2

Decreased frequency of classical monocytes in MPA compared to GPA patients. The frequencies of (a) classical (CD14⁺⁺CD16⁻), (b) intermediate (CD14⁺⁺CD16⁺), and (c) nonclassical (CD14⁻CD16⁺) monocytes in GPA and MPA patients. Analysis of monocytes in MPA patients compared to GPA patients evidenced a lower frequency of classical monocytes. No significant difference was shown between the two groups regarding intermediate and nonclassical monocytes. The Mann–Whitney U test was used to calculate the level of significance. Data are presented with medians. Indicates p-value < 0.01. WBC, white blood cell; GPA, granulomatosis with polyangiitis; MPA, microscopic polyangiitis, ns, not significant.

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