Disease Activity and Tendency to Relapse in ANCA-Associated Vasculitis Are Reflected in Neutrophil and Intermediate Monocyte Frequencies

Figure 3

Concentration of (a) mature (CD16^high) neutrophils, and frequencies of (b) total monocytes, and (c) intermediate (CD14⁺⁺CD16⁺) monocytes in 23 patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in active disease and remission. Patients with active disease present higher concentrations of mature neutrophils but lower frequencies of total monocytes and intermediate monocytes compared to patients in remission. Wilcoxon matched-pairs signed rank test was used to calculate the level of significance.and Indicate p-value < 0.05 and <0.001, respectively. WBC, white blood cell.

(a)

(b)

(c)