Disease Activity and Tendency to Relapse in ANCA-Associated Vasculitis Are Reflected in Neutrophil and Intermediate Monocyte Frequencies

Table 2

Leucocytes frequency in ANCA-associated vasculitis patients and healthy controls.

Cell type (% of WBC)	AAV patients (n = 105)	HC (n = 126)	p-Value
Basophils	0.8 (0.03–7.2)	0.7 (<0.001–2.5)	ns
Eosinophils	1.9 (0.02–20)	2.2 (0.2–16)	ns
Neutrophils CD16^dim	2.1 (0.06–16)	1.5 (0.008–10)	0.004
Mature neutrophils	36 (4.8–82)	25 (3.0–63)	<0.0001
Neutrophils CD177^+	17 (0–70)	11 (0–39)	<0.0001
Monocytes, total	4.2 (0.7–23)	3.8 (0.3–9.2)	0.04
Classical monocytes	3.8 (0.5–21.3)	3.4 (0.3–9)	ns
Intermediate monocytes	0.2 (0.04–1.3)	0.1 (0–1.02)	<0.0001
Nonclassical monocytes	0.2 (<0.1–0.9)	0.2 (0.01–1)	ns

Mann–Whitney U test was used to calculate the level of significance. Data are presented with medians (ranges). For the basophil analysis, 94 AAV patients and 67 HC were included. For eosinophil analysis, 92 AAV patients and 83 HC were included. AAV, antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis; HC, healthy controls; ns, not significant.