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Conditions | NCT number | Study title | Interventions | Phases | Study status | Enrollment | Study results |
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Multiple sclerosis | NCT02618902 | A “Negative” dendritic cell-based vaccine for the treatment of multiple sclerosis: a first-in-human clinical trial | Tolerogenic dendritic cells (tolDCs) | Phase 1 | Unknown | 9 | No |
NCT05451069 | Neurofilament light chain, chitinase-3 like-1 proteins, and plasmacytoid dendritic cells in multiple sclerosis | Neurofilament light chain, chitinase-3 like-1 protein levels, tolerogenic plasmacytoid dendritic cells | N/A | Not yet recruiting | 42 | No |
NCT02903537 | Tolerogenic dendritic cells as a therapeutic strategy for the treatment of multiple sclerosis patients (TOLERVIT-MS) | Autologous VitD3 tolerogenic monocyte-derived dendritic cells loaded with a pool of myelin peptides (tolDC-VitD3), interferon (IFN)-β | Phase 1 | Recruiting | 16 | No |
NCT04530318 | Dendritic cell therapy combined with immunomodulatory treatment in multiple sclerosis | Autologous peripheral blood differentiated adult dendritic cells expanded | Phase 2 | Recruiting | 45 | No |
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Multiple sclerosis, neuromyelitis optica | NCT02283671 | Treatment of multiple sclerosis and neuromyelitis optica with regulatory dendritic cell: clinical trial phase 1B | tolDCs loaded with myelin peptides | Phase 1 | Completed | 20 | No |
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Rheumatoid arthritis | NCT03337165 | Autologous tolerogenic dendritic cells for treatment of patients with rheumatoid arthritis | tolDCs | Phase 1 | Completed | 10 | No |
NCT01352858 | Autologous tolerogenic dendritic cells for rheumatoid arthritis (AutoDECRA) | tolDCs, arthroscopy, saline irrigation alone | Phase 1 | Unknown | 15 | No |
NCT05251870 | Tolerogenic dendritic cell therapy for rheumatoid arthritis | Autologous mature tolerogenic monocyte-derived dendritic cells loaded with the B29 peptide of HSP70 | Phase 1/ phase 2 | Recruiting | 18 | No |
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Type 1 diabetes mellitus | NCT05207995 | The treatment of patients with type 1 diabetes mellitus with autologous tolerogenic dendritic cells | Autologous tolerogenic dendritic cells | Phase 1/ phase 2 | Not yet recruiting | 30 | No |
NCT01947569 | Dendritic cells for type 1 diabetes mellitus (T1DM) therapy | Immunoregulatory dendritic cells (iDCs) | Phase 1/ phase 2 | Unknown | 90 | No |
NCT00445913 | Autologous dendritic cell therapy for type 1 diabetes suppression: a safety study | Diabetes-suppressive dendritic cell vaccine | Phase 1 | Completed | 10 | No |
NCT02354911 | Autologous immunoregulatory dendritic cells for type 1 diabetes therapy | iDCs | Phase 2 | Unknown | 24 | No |
NCT04590872 | An immunotherapy vaccine (PIpepTolDC) for the treatment of patients with type 1 diabetes | tolDCs vaccine | Phase 1 | Recruiting | 7 | No |
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