Research Article
HLA-DQB1 Allele Polymorphism Associated with Oral Submucous Fibrosis in Hunan, China
Table 2
Distribution of human leukocyte antigen (HLA)-DQB1 alleles in oral submucous fibrosis (OSF) cases and controls.
| | Alleles | OSF (n = 44) | Controls (n = 44) | χ2 | P | Pc | | Positive (n) | Frequency (%) | Positive (n) | Frequency (%) |
| | DQB102 : 01 | 11 | 25.0 | 14 | 31.8 | 0.503 | 0.478a | 0.636 | | DQB103 : 01 | 44 | 100 | 44 | 100 | — | — | — | | DQB103 : 02 | 44 | 100 | 44 | 100 | — | — | — | | DQB103 : 03 | 9 | 20.5 | 11 | 25.0 | 0.259 | 0.611a | 0.799 | | DQB104 : 01 | 0 | 0.0 | 0 | 0.0 | — | — | — | | DQB104 : 02 | 0 | 0.0 | 0 | 0.0 | — | — | — | | DQB105 : 01 | 3 | 6.8 | 2 | 4.5 | 0.000 | 1.000b | 1.000 | | DQB105 : 02 | 16 | 36.4 | 6 | 13.6 | 6.061 | 0.014a | 0.027 | | DQB105 : 03 | 26 | 59.1 | 31 | 70.5 | 1.245 | 0.265a | 0.372 | | DQB106 : 01 | 0 | 0.0 | 0 | 0.0 | — | — | — | | DQB106 : 02 | 4 | 9.1 | 2 | 4.5 | 0.715 | 0.398b | 0.672 | | DQB106 : 03 | 2 | 4.5 | 0 | 0.0 | 0.512 | 0.474b | 0.474 | | DQB106 : 04 | 2 | 4.5 | 0 | 0.0 | 0.512 | 0.474b | 0.474 |
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Note: Pc: corrected P value; aPearson chi-square test; bcorrected with Yates continuity correction. The bold values are statistically significant.
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