Using the RISK-PCI Score in the Long-Term Prediction of Major Adverse Cardiovascular Events and Mortality after Primary Percutaneous Coronary Intervention
Table 3
Baseline characteristics of analyzed patients according to 1-year and 6-year MACE and mortality.
Variable
1-year MACE
6-year MACE
1-year mortality
6-year mortality
No N = 1867
Yes N = 229
value
No N = 1811
Yes N = 285
value
No N = 1968
Yes N = 128
value
No N = 1945
Yes N = 151
value
Age, med (IQR)
58 (51, 68)
63 (54, 73)
<0.001
59 (51, 68)
63 (54, 73)
<0.001
58 (51, 68)
71 (61, 78)
<0.001
59 (61, 68)
71 (60, 77)
<0.001
Males (%)
1361 (72.9)
154 (67.1)
0.031
1320 (72.9)
193 (67.9)
0.027
1435 (72.9)
80 (62.3)
0.003
1418 (72.9)
96 (63.5)
<0.001
Previous MI (%)
189 (10.1)
39 (17.2)
<0.001
177 (9.8)
49 (17.1)
<0.001
203 (10.3)
24 (18.6)
<0.001
198 (10.2)
26 (17.5)
<0.001
Previous PCI (%)
48 (2.6)
9 (3.8)
0.179
45 (2.5)
11 (3.8)
0.149
49 (2.5)
6 (4.4)
0.143
53 (2.7)
5 (3.6)
0.376
Diabetes (%)
353 (18.9)
63 (27.4)
<0.001
323 (17.8)
77 (27.1)
<0.001
356 (18.1)
43 (33.8)
<0.001
354 (18.5)
48 (31.9)
<0.001
Hypertension (%)
1249 (66.9)
163 (71.2)
0.164
1188 (65.6)
208 (72.9)
0.013
1303 (66.2)
92 (71.6)
0.310
1328 (68.3)
111 (72.9)
<0.001
Hyperlipidemia (%)
1150 (61.6)
116 (50.8)
<0.001
1111 (61.4)
155 (54.4)
0.009
1214 (61.7)
52 (40.9)
<0.001
1241 (63.8)
67 (44.6)
<0.001
Smoking (%)
1041 (55.8)
89 (38.9)
<0.001
1010 (55.8)
120 (42.1)
<0.001
1092 (55.5)
39 (30.6)
<0.001
1120 (57.6)
50 (33.3)
<0.001
Family history (%)
640 (34.3)
15 (6.4)
0.002
625 (34.5)
75 (26.3)
0.001
673 (34.2)
29 (20.2)
<0.001
498 (25.6)
21 (20.3)
<0.001
Pain duration med (IQR)
2.5 (1.5, 4.5)
3.5 (2, 6.5)
<0.001
2.5 (1.5, 4.5)
3.5 (2, 6.5)
<0.001
2.5 (1.5, 4)
3 (2, 5.5)
<0.001
2.5 (1.5, 4.5)
3 (2, 6.5)
<0.001
KillipII and III at admission (%)
183 (9.8)
89 (38.9)
<0.001
176 (9.7)
95 (33.3)
<0.001
193 (9.8)
74 (57.9)
<0.001
196 (10.1)
75 (49.6)
<0.001
Systolic pressure (IQR)
140 (120, 150)
130 (110, 150)
<0.001
140 (120, 150)
130 (110, 150)
<0.001
140 (120, 130)
130 (105, 150)
<0.001
140 (120, 150)
130 (105, 145)
<0.001
Heart rate (IQR)
80 (70, 90)
80 (70, 100)
<0.001
80 (70, 90)
80 (70, 110)
<0.001
77 (68, 90)
90 (75, 110)
<0.001
80 (70, 90)
85 (70, 110)
<0.001
Anterior MI, n (%)
721 (38.6)
134 (58.4)
<0.001
697 (38.5)
154 (54.1)
<0.001
773 (39.3)
77 (60.1)
<0.001
790 (40.6)
86 (57.2)
<0.001
BBB,n (%)
50 (2.7)
35 (15.1)
<0.001
49 (2.7)
35 (12.3)
<0.001
57 (2.9)
26 (20.2)
<0.001
60 (3.1)
26 (17.1)
<0.001
3-vessel disease (%)
472 (25.3)
91 (39.6)
<0.001
455 (25.1)
107 (37.6)
<0.001
496 (25.2)
64 (50.3)
<0.001
508 (26.1)
70 (46.4)
<0.001
Left main stenosis, n (%)
114 (6.1)
20 (8.7)
0.072
110 (6.1)
24 (8.3)
<0.001
116 (5.9)
14 (10.9)
0.007
122 (6.3)
14 (9.1)
<0.001
Stent (%)
2432 (95.2)
193 (84.1)
<0.001
1723 (95.1)
246 (86.3)
<0.001
1866 (94.8)
140 (76.5)
<0.001
1910 (98.2)
120 (79.3)
<0.001
Postprocedural TIMI<3 (%)
83 (3.2)
43 (18.8)
<0.001
60 (3.3)
44 (15.3)
<0.001
65 (3.3)
37 (28.9)
<0.001
66 (3.4)
16 (10.8)
<0.001
CK, med (IQR)
1842 (9215, 3399)
2697 (1031, 5124)
<0.001
1820 (908, 3392)
2445 (1046, 4593)
<0.001
1864 (1007, 3387)
2456 (1051, 4033)
<0.001
1849 (925, 3471)
2189 (1004, 4355)
<0.001
Troponin I, med (IQR)
30.5 (9.8, 86.2)
41.3 (8.36, 11.89)
<0.001
30.6 (9.5, 86)
36.5 (8.4, 110.2)
<0.001
30.3 (9.5, 87.7)
47.4 (11.8, 111.6)
<0.001
30 (9.1, 86.1)
47 (12.5, 110.2)
<0.001
Haemoglobin g/L med (IQR)
141 (132, 152)
143 (130, 153)
0.050
142 (132, 153)
143 (129, 152)
<0.001
143 (132, 152)
136 (124, 149)
0.135
142 (132, 153)
135 (121, 147)
<0.001
LVEF med (IQR)
50 (44 55)
40 (30 50)
<0.001
50 (40, 55)
40 (35, 50)
<0.001
50 (40, 55)
30 (25, 40)
<0.001
50 (40, 55)
40 (25, 45)
<0.001
CrCl med (IQR)
92.4 (71.2, 114.9)
62.4 (45.2, 86.3)
<0.001
92.8 (71.8, 115.8)
77.8 (57.2, 97.4)
<0.001
91.11 (71.82, 111.37)
59.89 (45.32, 83.11)
<0.001
92.8 (71.8, 115.1)
63.3 (46.9, 90.2)
<0.001
RISK-PCI score, med (IQR)
3 (2, 5)
5.5 (4, 8)
<0.001
3 (2, 4.5)
5 (3, 7.5)
<0.001
3 (2, 5)
7.5 (5, 9.5)
<0.001
3 (2, 5)
7 (4.5, 9.5)
<0.001
Hours from symptom onset to first medical contact; at admission; MACE = major adverse cardiovascular events; BBB = bundle branch block; MI = myocardial infarction; PCI = percutaneous coronary intervention; TIMI = Thrombolysis in Myocardial Infarction; LVEF = left ventricular ejection fraction; CrCl = creatinine clearance ml/min; MACE = major adverse cardiovascular events.
