Research Article

Long-Term Clinical Outcomes for Non-ST Elevation Acute Coronary Syndrome Patients with High-Risk Angiographic Findings Undergoing Percutaneous Coronary Intervention

Table 1

Baseline patient characteristics.

HRCA (n = 3752)LRCA (n = 1232) value

Age59.49 ± 10.0457.87 ± 10.15<0.001
Female, n(%)962 (25.6)320 (26.0)0.816
Body mass index, kg/m225.84 ± 3.1825.88 ± 3.260.680
Risk factors and history, n (%)
 Smoker2152 (57.4)691 (56.1)0.435
 Diabetes1173 (31.3)299 (24.3)<0.001
 Hypertension2508 (66.8)780 (63.3)0.023
 Hyperlipidemia2533 (67.5)825 (67.0)0.723
 Prior myocardial infarction586 (15.6)177 (14.4)0.290
 Prior stroke461 (12.3)103 (8.4)<0.001
 Peripheral vascular disease105 (2.8)19 (1.5)0.014
 Family history of CAD924 (24.6)312 (25.3)0.633
Laboratory tests
 Leukocyte, ×109/L6.83 ± 1.776.81 ± 1.770.700
 Platelet, ×109/L203.44 ± 53.52201.92 ± 48.930.379
 Hemoglobin, g/L140.44 ± 15.96141.40 ± 16.390.072
 Creatinine, umol/L75.55 ± 16.0373.86 ± 16.200.001
 GFR, ml/min/1.73 m290.28 ± 15.1192.87 ± 14.69<0.001
 LVEF, %63.56 ± 6.6964.07 ± 6.480.023
 Glucose, mg/dL6.17 ± 2.045.88 ± 1.70<0.001
 CK-MB, IU/L11.83 ± 12.9111.96 ± 10.730.742
 BUN, mmol/L5.70 ± 1.685.61 ± 1.650.102
 hsCRP3.18 ± 3.682.76 ± 3.41<0.001
Clinical presentation
 NSTEMI365 (9.7)110 (8.9)0.407
 UA3387 (90.3)1122 (91.1)0.407
Medication at discharge, n (%)
 Aspirin3708 (98.8)1215 (98.6)0.566
 Clopidogrel3741 (99.7)1230 (99.8)0.747
 Ticagrelor10 (0.3)2 (0.2)0.517
β-Blockers3356 (89.4)1053 (85.5)<0.001
 Calcium channel blockers2163 (57.6)682 (55.4)0.158
 Nitrates3700 (98.6)1199 (97.3)0.002
 Statins3609 (96.2)1182 (95.9)0.696

Values are mean ± SD or n (%). HRCA = high-risk coronary anatomy; CAD = coronary artery disease; GFR = glomerular filtration rate; LVEF = left ventricular ejection fraction; CK-MB = creatine kinase-muscle/brain; BUN = blood urea nitrogen; hsCRP = high-sensitivity C-reactive protein; STEMI = ST elevation myocardial infarction; NSTEMI = non-ST elevation myocardial infarction; UA = unstable angina.