Clinical Outcomes of Drug-Eluting versus Bare-Metal In-Stent Restenosis after the Treatment of Drug-Eluting Stent or Drug-Eluting Balloon: A Systematic Review and Meta-Analysis

Table 1

Main characteristics of the included studies.

First author	Published year	Study type	TPN	Treatment	FU time	Endpoints
Berta	2014	Observational	82	DEB	28 months	TLR, ST, MI, MACE, death
Lee	2016	Observational	230	DEB	12 months	RE-ISR, MI, MACE, death, CD
Alfonso	2017	Observational	249	DEB	12 months	TLR, TVR, ST, MI, MACE, death, CD
Beatriz	2011	Observational	126	DEB	12 months	TLR, ST, MI, MACE, death, CD
Markus	2016	Observational	135	DEB	12 months	RE-ISR, TLR
Christoph	2012	Observational	81	DEB	12 months	TLR, TVR, ST, MI, MACE, death, CD
Ralph	2014	Observational	918	DEB	13 months	TLR, TVR, ST, MI, MACE, death, CD
Daniel	2009	Observational	238	DES	12 months	TVR, ST, MI, MACE, death
Robert	2013	Observational	650	DES	12 months	TLR, ST, MI, MACE, death
Negar	2012	Observational	194	DES	12 months	TLR, TVR, MI, MACE, CD
Jose	2009	Observational	216	DES	72 months	TLR, ST, MI, CD
Heng	2010	Observational	97	DES	28 months	TVR, MI, MACE, death
Fernando	2016	Observational	249	DES	12 months	TLR, TVR, ST, MI, MACE, death, CD
Mohammad	2012	Observational	94	DES	12 months	TLR, ST, MI, MACE, death, CD
Cheol	2008	Observational	295	DES	32 months	TLR, ST, MI, death, CD
Yan	2013	Observational	388	DES	42 months	TLR, TVR, ST, MI, MACE, death, CD
Kensaku	2010	Observational	158	DES	8 months	TLR, TVR, RE-ISR, MACE
Alexandre	2012	Observational	1590	DES	12 months	TLR, ST, MI, MACE, death
Gert	2013	Observational	266	DES	24 months	TLR, TVR, ST, MI, MACE, death, CD

TPN: total patient number; FU: follow-up; DEB: drug-eluting balloon; DES: drug-eluting stent; TLR: target lesion revascularization; TVR: target vessel revascularization; CD: cardiac death; MI: myocardial infarction; ST: stent thrombosis; RE-ISR: re-in-stent restenosis; MACE: major adverse cardiovascular event.