Association of Side-Branch Treatment and Patient Factors in Left Anterior Descending Artery True Bifurcation Lesions: Analysis from the GRAND-DES Pooled Registry
Table 2
Baseline characteristics according to SB treatment in the low-risk group.
ACEF-LOW (ACEF score <1.22)
value
SB treatment (n = 318)
No SB treatment (n = 284)
Patient factors
Sex (male, %)
236 (74.2)
199 (70.1)
0.30
Age (years)
59.7 ± 10.2
62.3 ± 9.6
<0.01
BMI (kg/m2)
24.6 ± 3.2
24.8 ± 3.0
0.47
Current smoker
100 (31.4)
86 (30.3)
0.83
Comorbidities
Hypertension
182 (57.2)
174 (61.3)
0.36
Diabetes
95 (29.9)
104 (36.6)
0.10
Dyslipidemia
193 (60.7)
184 (64.8)
0.34
CVA
17 (5.3)
19 (6.7)
0.60
PAD
3 (0.9)
3 (1.1)
1.00
FHx of CHD
32 (10.1)
21 (7.4)
0.31
Previous MI
13 (4.1)
9 (3.2)
0.70
Presentation with MI
70 (22.0)
52 (18.3)
0.31
ACS
165 (51.9)
150 (52.8)
0.88
LV dysfunction (EF<40%)
2 (0.6)
1 (0.4)
1.00
Serum creatinine (mg/dL)
0.9 (0.8–1.1)
0.9 (0.8–1.1)
0.90
History of PCI or CABG
22 (6.9)
20 (7.0)
1.00
Lesion characteristics
3VD
61 (19.2)
93 (32.7)
<0.01
Medina class
0.66
1, 1, 1
230 (72.3)
213 (75.0)
1, 0, 1
25 (7.9)
23 (8.1)
0, 1, 1
63 (19.8)
48 (16.9)
Calcified lesion
30 (9.4)
47 (16.5)
0.01
Tortuous lesion
45 (14.2)
76 (26.8)
<0.01
Procedure characteristics
SB balloon angioplasty
213 (67.0)
0 (0)
SB stenting
105 (33.0)
0 (0)
IVUS-guidance
159 (50.0)
126 (44.4)
0.19
GP IIb-IIIa inhibitor
11 (3.5)
6 (2.1)
0.45
Medications
RAS inhibitor
204 (64.2)
179 (63.0)
0.84
Beta-blocker
209 (65.7)
178 (62.7)
0.49
ACEF score
0.94 ± 0.15
0.99 ± 0.14
<0.01
Values are mean ± SD, median (interquartile ranges, 25th-75th), or n (%) (per-patient analysis). SB, side branch; BMI, body mass index; CVA, cerebrovascular accident; PAD, peripheral artery disease; FHx, family history; CHD, coronary heart disease; MI, myocardial infarction; ACS, acute coronary syndrome; LV, left ventricle; EF, ejection fraction; PCI, percutaneous coronary intervention; CABG, coronary artery bypass graft surgery; 3VD, three-vessel disease; IVUS, intravascular ultrasound; GP, glycoprotein; RAS, renin-angiotensin system; ACEF, age, creatinine, and ejection fraction.
