Association of Side-Branch Treatment and Patient Factors in Left Anterior Descending Artery True Bifurcation Lesions: Analysis from the GRAND-DES Pooled Registry
Table 3
Three-year composite and individual outcomes according to SB treatment.
Whole study population
ACEF-LOW group
Outcomes (n, %)
SB treatment (N = 548)
No SB treatment (N = 541)
Adjusted HR†
SB treatment (N = 318)
No SB treatment (N = 284)
Adjusted HR†
HR (95% CI)
value
HR (95% CI)
value
Target lesion failure∗
36 (6.6)
50 (9.2)
0.75 (0.44–1.28)
0.29
9 (2.8)
21 (7.4)
0.43 (0.19–0.96)
0.04
Cardiac death
16 (2.9)
31 (5.7)
0.59 (0.27–1.28)
0.18
3 (0.9)
7 (2.5)
0.57 (0.14–2.32)
0.43
Target vessel MI
3 (0.5)
5 (0.9)
0.42 (0.07–2.42)
0.33
2 (0.6)
4 (1.4)
0.64 (0.11–3.75)
0.62
CD-TLR
17 (3.1)
20 (3.7)
0.75 (0.35–1.62)
0.46
4 (1.3)
15 (5.3)
0.24 (0.08–0.75)
0.01
Definite/probable ST
3 (0.5)
3 (0.6)
0.89 (0.07–11.83)
0.93
0
1 (0.4)
—
—
All-cause death
24 (4.4)
47 (8.7)
0.69 (0.38–1.27)
0.24
5 (1.6)
8 (2.8)
0.97 (0.30–3.08)
0.95
Any MI
6 (1.1)
7 (1.3)
0.78 (0.23–2.65)
0.70
4 (1.3)
5 (1.8)
0.89 (0.23–3.47)
0.87
Any repeat revascularization
56 (10.2)
50 (9.2)
1.12 (0.72–1.74)
0.62
25 (7.9)
29 (10.2)
0.82 (0.47–1.44)
0.49
Target vessel revascularization
28 (5.1)
30 (5.5)
0.96 (0.52–1.78)
0.90
10 (3.1)
20 (7.0)
0.48 (0.22–1.05)
0.07
Composite of cardiac death, target vessel MI, and CD-TLR. †Adjusted for sex, severe lesion calcification, tortuous lesion, 3-vessel disease, and ACEF score. SB, side branch; HR, hazard ratio; MI, myocardial infarction; CD-TLR, clinically driven target lesion revascularization; ST, stent thrombosis.
