Research Article

Impact of Lesion Preparation Technique on Side Branch Compromise in Calcified Coronary Bifurcations: A Subgroup Analysis of the PREPARE-CALC Trial

Table 2

Angiographic and procedural characteristics (n = 115 lesions).

SCB (n = 47)RA (n = 68) value

Angiographic characteristics
Location0.84
 Left main12 (25.5%)15 (22.1%)
 Left anterior descending28 (59.6%)43 (63.2%)
 Left circumflex5 (10.6%)8 (11.8%)
 Right coronary artery2 (4.3%)2 (2.9%)
Reference vessel diameter (mm)3.27 ± 0.463.26 ± 0.450.87
Lesion length (mm)26.06 ± 13.8427.34 ± 14.830.64
Diameter stenosis (%)83.57 ± 8.9985.94 ± 9.630.19
Ostial location15 (31.9%)31 (45.6%)0.14
Angle > 70% between MB and SB18 (38.3%)23 (33.8%)0.62
SB > 2 mm41 (87.2%)54 (79.4%)0.28
True bifurcation lesions23 (49%)29 (43%)0.50
Medina classification
 1.1.019 (40.4%)30 (44.1%)
 1.1.118 (38.3)26 (38.2%)
 1.0.12 (4.2%)1 (1.5%)
 1.0.001 (1.5%)
 0.1.12 (4.2%)1 (1.5%)
 0.1.05 (10.6%)8 (11.7%)
 0.0.11 (2.1%)1 (1.5%)

Procedural characteristics
SCB or RA in SB3 (6.3%)2 (2.9%)0.38
Wire in SB28 (59.7%)36 (52.9%)0.48
SB kissing or balloon dilation after stenting17 (36.2%)26 (38.2%)0.82
Stenting technique0.75
 One-stent technique36 (76.6%)51 (75%)
 Two-stent technique10 (21.3%)17 (25%)
  Culotte6 (12.8%)6 (8.8%)
  T-stenting1 (2.1%)2 (2.9%)
  DK-crush01 (1.5%)
  Minicrush1 (2.1%)1 (1.5%)
  TAP stenting2 (4.2%)7 (10.3%)
 No stent1 (2.1%)0
Stenting of the SB10 (21.3%)17 (25%)0.85
 Elective7 (14.9%)11 (16.2%)
 Bailout3 (6.4%)6 (8.8%)
POT28 (59.6%)42 (61.8%)0.81
LMT involvement during the PCI21 (44.7%)28 (41.2%)0.71
Cutting/scoring balloon diameter (mm)3.04 ± 0.32
Cutting/scoring balloon pressure (atm)15.30 ± 2.3
Starting burr size (mm)1.51 ± 0.17
Max. burr size (mm)1.53 ± 0.17
Use of >1 burr6 (8.8%)-—
Rotational speed (RPM)164,895 ± 22,038
Number of predilatation balloons1.74 ± 0.851.75 ± 0.980.95
Max. predilatation balloon diameter (mm)2.78 ± 0.472.90 ± 0.380.16
Max. predilatation balloon pressure (atm)18.22 ± 3.4319.50 ± 5.080.20
No. of stents/lesions1.85 ± 0.921.50 ± 0.680.02
Total stent length/lesion (mm)37.09 ± 17.6333.88 ± 15.710.31
Min. stent diameter (mm)3.14 ± 0.413.08 ± 0.470.50
Max. stent diameter (mm)3.43 ± 0.413.30 ± 0.400.09
Max. stent implantation pressure (atm)16.61 ± 2.8316.92 ± 3.320.57
Balloon postdilatation41 (87.2%)62 (91.1%)0.50
Max. postdilatation balloon diameter (mm)3.56 ± 0.563.65 ± 0.530.06
Max. postdilatation balloon pressure (atm)20.54 ± 3.2321.13 ± 4.100.44
Procedural result on SB
Compromised at any time during the procedure25 (53.2%)28 (41.2%)0.20
Compromised at the end of the procedure15 (31.9%)5 (7.4%)0.001
Mechanism of SB compromise
 Significant stenosis13 (27.7%)4 (5.9%)
 Dissection2 (4.3%)1 (1.5%)
 TIMI flow <3 in SB4 (8.5%)2 (3%)

Values are n (%) or mean ± SD; DK-crush = double kissing crush; MB = main branch; LMT = left main trunk; POT = proximal optimization technique; RPM = rotations per minute; RA = rotational atherectomy; SB = side branch; SCB = scoring/cutting balloon; TAP = T-and-protrusion technique. True bifurcation lesions: Medina 1.1.1, 1.0.1, and 0.1.1.