Research Article

Ezetimibe Improves Rosuvastatin Effects on Inflammation and Vascular Endothelial Function in Acute Coronary Syndrome Patients Undergoing PCI

Table 1

Baseline characteristics of the study subjects.

Rosuvastatin (n = 90)Ezetimibe/rosuvastatin (n = 81) value

Male, n (%)63 (70.0%)55 (67.9%)0.77
Age (years)64.08 ± 10.4561.74 ± 8.780.12
BMI (kg/m2)24.36 ± 3.1824.24 ± 3.490.82
Current smokers, n (%)44 (48.9%)34 (42.0%)0.37
Diabetes mellitus, n (%)30 (33.3)29 (35.8)0.74
Hypertension, n (%)50 (55.5)41 (50.6)0.52
Dyslipidemia, n (%)37 (41.1)23 (28.4)0.08
LVEF (%)59.00 ± 7.4760.17 ± 7.870.32

Presentation of ACS
 STEMI, n (%)24 (26.7)16 (19.8)0.29
 NSTEMI, n (%)13 (14.4)6 (7.4)0.14
 UA, n (%)53 (58.9)59 (72.8)0.06

Previous medications
 Aspirin, n (%)10 (11.1)7 (8.6)0.59
 Clopidogrel, n (%)5 (5.6)3 (3.7)0.57
 Beta-blockers, n (%)10 (11.1)5 (6.2)0.25
 ACE inhibitors, n (%)14 (15.6)9 (11.1)0.40

Values are presented as n (%) or mean ± standard deviation. BMI, body mass index; LVEF, left ventricular ejection fraction; ACS, acute coronary syndrome; STEMI, ST-segment elevation myocardial infarction; NSTEMI, none ST-segment elevation myocardial infarction; UA, unstable angina; ACE, angiotensin-converting enzyme.