Research Article

Outcomes of Percutaneous Coronary Intervention in Patients with Spontaneous Coronary Artery Dissection

Table 1

Baseline and hospital characteristics.

Mean ± SD, median (Q1, Q3), or n (%)PCI (n = 75)No PCI (n = 328) value

Age48.9 ± 10.153.1 ± 9.60.001
Female71 (94.7)297 (90.5)0.363
BMI22.7(20.7, 26.4)24.7 (21.5, 28.8)0.016
Race0.890
Caucasian63 (84.0)271 (82.6)
East Asian8 (10.7)34 (10.4)
South Asian3 (4.0)16 (4.9)
African Canadian1 (1.3)2 (0.6)
First Nation0 (0)3 (0.9)
Family history of CAD23 (30.7)114 (34.8)0.589
HTN19 (25.3)127 (38.7)0.033
Hyperlipidemia20 (26.7)81 (24.7)0.768
DM3 (4.0)13 (4.0)>0.9
Current smoker8 (10.7)34 (10.4)0.892
Previous MI2 (2.7)16 (4.9)0.545
History of CVA4 (5.3)11 (3.4)0.495
Depression17 (22.7)74 (22.6)>0.9
Anxiety12 (16.2)44 (13.4)0.577

Precipitating/predisposing factors
Emotional stress36 (48.0)179 (54.6)0.31
Physical stress21 (28.0)89 (27.1)0.89
Isometric >50 pounds6 (28.6)32 (36.0)0.62
Connective tissue disease6 (8.0)13 (4.0)0.13
Systemic inflammation6 (8.0)15 (4.6)0.25
Active hormonal treatment14 (18.7)34 (10.4)0.073
Postmenopausal36/71 (50.7)201/297 (67.7)0.009
Peripartum3/71 (4.2)6/297 (2.0)0.38
Fibromuscular dysplasia35 (46.7)210 (64.0)0.008

Hospital presentation
STEMI38 (50.7)65 (19.8)<0.001
NSTEMI37 (49.3)263 (80.2)<0.001
Peak trop I (median, IQR)16.0 (3.2, 40.2)6.1 (1.8, 15.1)0.001
Peak high-sensitive trop T990 (269, 5507)572 (263, 1916)0.399
VT/VF10 (13.3)28 (8.6)0.272
EF (%)50 (40, 50)58 (50, 63)<0.001
EF <50%25 (40.3)45 (18.1)0.001
Hospital length of stay (days)3 [3, 5]3 [3, 4]0.038