Research Article
Atrial Fibrillation is Associated with Femoropopliteal Totally Occlusive In-Stent Restenosis: A Single-Center, Retrospective, Observational Study
Table 3
Predictors of totally occlusive ISR within 3 years.
| Variables | Univariate analysis | Multivariate analysis | Hazard ratio | 95% CI | value | Hazard ratio | 95% CI | value |
| Age (per 1 increase) | 1.01 | 0.97–1.06 | 0.12 | — | — | — | Female | 1.78 | 1.08–2.92 | 0.02 | 1.63 | 0.99–2.69 | 0.05 | Nonambulatory | 2.27 | 1.20–4.01 | 0.01 | 1.68 | 0.88–2.99 | 0.11 | Dyslipidemia | 1.41 | 0.75–1.74 | 0.26 | — | — | — | Diabetes mellitus | 1.12 | 0.68–1.86 | 0.65 | — | — | — | Hemodialysis | 0.76 | 0.32–1.55 | 0.48 | — | — | — | Atrial fibrillation | 2.31 | 1.24–3.75 | 0.008 | 2.1 | 1.18–3.57 | 0.01 | Low EF (<40%) | 1.58 | 0.50–4.82 | 0.23 | — | — | — | Critical limb ischemia | 1.54 | 0.89–2.57 | 0.12 | — | — | — | Dual-antiplatelet therapy | 1.36 | 0.78–2.52 | 0.28 | — | — | — | Chronic total occlusion | 3.01 | 1.75–5.48 | <0.001 | 1.97 | 1.02–3.96 | 0.04 | TASC C/D lesions | 2.91 | 1.72–5.09 | <0.001 | 1.81 | 0.97–3.51 | 0.06 | PACCS grade 4 | 0.79 | 0.21–1.68 | 0.45 | — | — | — | Run-off grade 0 | 1.42 | 0.71–2.53 | 0.41 | — | — | — | Poor run-off | 1.26 | 0.63–2.40 | 0.26 | — | — | — | Drug-eluting stent implantation | 1.03 | 0.55–2.15 | 0.93 | — | — | — |
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EF, ejection fraction; TASC, Trans-Atlantic Inter-Society Consensus; PACCS, peripheral artery calcification scoring system.
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