Research Article
Evaluate Short-Term Outcomes of abciximab in ST-Segment Elevation Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention: A Meta-Analysis of Randomized Clinical Trials
Table 1
Characteristics of the trials included.
| Study | Journal | Publication year | No. of centers | No.of patients | Patients | Randomization | Types of stent | Time of abciximab | Follow-up duration |
| Antoniucci et al. [27] | JACC | 2003 | — | 400 | With CS | Abciximab (n = 200) vs. placebo (n = 200) | BMS | Before PCI | 30 days 6 months | Brener et al. [22] | Circulation | 1998 | 36 | 483 | No CS | Abciximab (n = 241) vs. placebo (n = 242) | BMS | Before angiography | 30 days 6 months | Ernst et al. [23] | JACC | 2004 | Single-center | 119 | No CS | Abciximab (n = 30) vs. placebo (n = 89) | — | Before PCI | In-hospital 30 days | Mehilli et al. [24] | Circulation | 2009 | 5 | 800 | No CS | Abciximab (n = 401) vs. placebo (n = 399) | BMS DES | Before angiography | 30 days | Montalescot et al. [4] | N Engl J Med | 2001 | 26 | 300 | With CS | Abciximab (n = 149) vs. placebo (n = 151) | BMS | Before angiography | 30 days 6 months | Neumann et al. [25] | Circulation | 1998 | — | 200 | — | Abciximab (n = 102) vs. placebo (n = 98) | BMS | — | 14 days 30 days | Neumann et al. [3] | JACC | 2000 | — | 401 | — | Abciximab (n = 201) vs. placebo (n = 200) | BMS | — | 30 days 1 year | Petronio et al. [28] | Am Heart J | 2005 | — | 60 | No CS | Abciximab (n = 30) vs. placebo (n = 30) | BMS | Before PCI | 30 days 6 months | Tcheng et al. [26] | Circulation | 2003 | 76 | 2082 | No CS | Abciximab (n = 1052) vs. placebo (n = 1030) | BMS | — | 30 days 1 year | Zorman et al. [29] | Am J Cardiol | 2002 | — | 163 | With CS | Abciximab (n = 112) vs. placebo (n = 51) | BMS | Both | In-hospital 6 months |
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CS: cardiac shock; BMS: bare-metal stent; DES: drug-eluting stent; PCI, percutaneous coronary intervention.
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