Research Article

Evaluate Short-Term Outcomes of abciximab in ST-Segment Elevation Myocardial Infarction Patients Undergoing Percutaneous Coronary Intervention: A Meta-Analysis of Randomized Clinical Trials

Table 1

Characteristics of the trials included.

StudyJournalPublication yearNo. of centersNo.of patientsPatientsRandomizationTypes of stentTime of abciximabFollow-up duration

Antoniucci et al. [27]JACC2003400With CSAbciximab (n = 200) vs. placebo (n = 200)BMSBefore PCI30 days 6 months
Brener et al. [22]Circulation199836483No CSAbciximab (n = 241) vs. placebo (n = 242)BMSBefore angiography30 days 6 months
Ernst et al. [23]JACC2004Single-center119No CSAbciximab (n = 30) vs. placebo (n = 89)Before PCIIn-hospital 30 days
Mehilli et al. [24]Circulation20095800No CSAbciximab (n = 401) vs. placebo (n = 399)BMS DESBefore angiography30 days
Montalescot et al. [4]N Engl J Med200126300With CSAbciximab (n = 149) vs. placebo (n = 151)BMSBefore angiography30 days 6 months
Neumann et al. [25]Circulation1998200Abciximab (n = 102) vs. placebo (n = 98)BMS14 days 30 days
Neumann et al. [3]JACC2000401Abciximab (n = 201) vs. placebo (n = 200)BMS30 days 1 year
Petronio et al. [28]Am Heart J200560No CSAbciximab (n = 30) vs. placebo (n = 30)BMSBefore PCI30 days 6 months
Tcheng et al. [26]Circulation2003762082No CSAbciximab (n = 1052) vs. placebo (n = 1030)BMS30 days 1 year
Zorman et al. [29]Am J Cardiol2002163With CSAbciximab (n = 112) vs. placebo (n = 51)BMSBothIn-hospital 6 months

CS: cardiac shock; BMS: bare-metal stent; DES: drug-eluting stent; PCI, percutaneous coronary intervention.