Drug-Coated Balloons for Acute Myocardial Infarction: A Metaanalysis of Randomized Clinical Trials

Table 1

Characteristics of randomized controlled trials included in the metaanalysis.

Author/acronym	Years	Lesion characteristic	No. of patents			Follow-up period (month)		Primary end-point	Definition of MACEs
			DCB	DES	BMS	Angiographic	Clinical
Gobic et al. [16]	2017	STEMI	38	37	NA	6	6	MACEs	Death, TLR, ST
REVELATION [17]	2019	NSTEMI	104	51	69	NA	9	TLF	All-cause death, MI, TLR, stroke, PCI at other vessels
PEPCAD NSTEMI [18]	2020	STEMI	60	60	NA	9	9	FFR	Death, MI, TLR
Hao et al. [19]	2021	STEMI	38	42	NA	12	12	LLL	Death, MI, TLR

DCB: drug-coated balloon; DES: drug-eluting stent; BMS: bare-metal stent; MACEs: major adverse cardiac events; STEMI: ST-segment elevation myocardial infarction; TLR: target lesion revascularization; ST: stent thrombosis; NSTEMI: non-ST elevation myocardial infarction; TLF: target lesion failure; MI: myocardial infarction; PCI: percutaneous coronary intervention; FFR: fractional flow reserve; LLL: late lumen loss.