Journal of Interventional Cardiology

Research Article

The Impact of Kidney Function on the Slow-Flow/No-Reflow Phenomenon in Patients Treated with Primary Percutaneous Coronary Intervention: Registry Analysis

Table 4

Univariate and multivariate Cox regression analysis showing independent predictors for short- and long-term (one-year and eight-year) all-cause mortality.


Variable	Univariate analysis	value	Multivariate analysis	value
Variable	OR (95% CI)	value	OR (95% CI)	value

30-day all-cause mortality
Age, (years)	1.07 (1.06–1.09)	<0.001	1.03 (1.02–1.05)	<0.001
EF (%)	0.84 (0.82–0.85)	<0.001	0.87 (0.85–0.89)	<0.001
Slow-flow/no-reflow	11.28 (7.95–16.03)	<0.001	3.28 (2.10–5.12)	<0.001
Killip class >1 at admission	9.62 (8.24–12.5)	<0.001	2.68 (1.65–5.12)	<0.001
New-onset AF	5.91 (4.14–8.45)	<0.001	1.52 (1.10–2.34)	0.050
Diabetes	2.14 (1.72–3.19)	<0.001
eGFR <90 ml/min/m²	5.53 (3.15–8.71)	<0.001	1.75 (1.23–3.19)	0.025
Complete AV block at admission	3.60 (2.90–4.15)	<0.001
Previous MI	2.29 (1.34–3.59)	<0.001
One-year all-cause mortality
Age, (years)	1.07 (1.06–1.08)	<0.001	1.01 (1.03–1.05)	<0.001
EF (%)	0.87 (0.86–0.88)	<0.001	0.98 (0.89–0.92)	<0.001
Slow-flow/no-reflow	8.24 (5.72–11.92)	<0.001	2.21 (1.56–3.13)	<0.001
Killip class >1 at admission	8.21 (6.19–11.32)	<0.001	2.20 (1.56–3.08)	<0.001
eGFR <90 ml/min/m²	4.40 (3.08–6.44)	<0.001	1.61 (1.03–3.37)	0.034
New-onset AF	4.38 (3.18–6.87)	<0.001
Complete AV block at admission	3.19 (2.33–4.39)	<0.001
Diabetes	2.18 (1.65–2.94)	<0.001
Previous MI	2.07 (1.45–2.94)	<0.001
Eight-year all-cause mortality
Age, (years)	1.07 (1.06–1.08)	<0.001	1.04 (1.02–1.05)	<0.001
EF (%)	0.92 (0.91–0.94)	<0.001	0.91 (0.90–0.92)	<0.001
Slow-flow/no-reflow	8.24 (5.69–10.32)	<0.001	2.09 (1.49–2.89)	<0.001
Killip class >1 at admission	7.81 (3.79–10.87)	<0.001	1.74 (1.32–2.41)	<0.001
eGFR <90 ml/min/m²	4.45 (3.13–5.99)	<0.001	1.47 (1.07–2.02)	0.047
New onset AF	3.88 (2.87–5.3)	<0.001
Complete AV block at admission	2.52 (2.01–6.01)	<0.001
Diabetes	2.08 (1.52–2.72)	<0.001
Previous MI	2.00 (1.41–2.84)	<0.001

EF = left ventricular ejection fraction; AF = atrial fibrillation; MI = myocardial infarction; AV = atrioventricular; eGFR = estimated glomerular filtration rate.