Research Article
Impact of Laparoscopic Sleeve Gastrectomy on Thrombomodulin Concentration and Early Markers of Atherosclerosis
Table 2
The comparison of the clinical, laboratory, and echocardiographic parameters from baseline to the postoperative 6 months.
| | Baseline | Postoperative 6 months | Change (Δ) | value |
| Weight, kg | 129 ± 24 | 102 ± 21 | 27 ± 7 | <0.001 | Body mass index, kg/m2 | 47.1 ± 5.8 | 37.0 ± 5.6 | 10.1 ± 2.4 | <0.001 | Fasting plasma glucose, mg/dl | 102 ± 17 | 99 ± 16 | 3.3 ± 36 | 0.102 | Mean platelet volume, fL | 7.5 ± 1.6 | 7.8 ± 1.3 | −0.3 ± 1.67 | 0.120 | NLR | 1.6 ± 0.8 | 1.8 ± 0.8 | −0.2 ± 1 | 0.172 | HDL cholesterol, mg/dL | 35.1 ± 11.2 | 41.5 ± 10.7 | −6.3 ± 19.4 | 0.006 | Triglyceride, mg/dL | 247 ± 69 | 176 ± 67 | 70 ± 112 | <0.001 | LDL cholesterol, mg/dL | 109 ± 27 | 89 ± 16 | 19 ± 34 | 0.001 | EF, % | 62.4 ± 2.4 | 62.5 ± 2.4 | −0.1 ± 1 | 0.534 | SBP, mmHg | 136 ± 13 | 123 ± 15 | 13 ± 20 | <0.001 | DBP, mmHg | 80 ± 9 | 75 ± 8 | 5 ± 11 | 0.022 | CIMT, mm | 1.06 ± 0.05 | 0.98 ± 0.14 | 0.1 ± 0.2 | 0.003 | ABI | 0.85 ± 0.08 | 0.95 ± 0.05 | −0.1 ± 0.1 | <0.001 | Thrombomodulin, ng/mL | 3.3 ± 0.8 | 2.2 ± 0.4 | 1.1 ± 0.7 | <0.001 |
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Data are presented as the mean ± standard deviation. ABI = Ankle-brachial index; CIMT = Carotid intima-media thickness; DBP = Diastolic blood pressure; EF = Ejection fraction; HDL = High-density lipoprotein; LDL = Low-density lipoprotein; NLR = Neutrophil to lymphocyte ratio; SBP = Systolic blood pressure; TG = Trigylceride.
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