Journal of Interventional Cardiology

Research Article

Sex Differences and Temporal Trends in Hospitalization for Catheter Ablation of Nonvalvular Atrial Fibrillation: A Single-Center Experience for 15 Years

Table 2

Temporal trends in clinical features of women and men.
 2005–20072008–20102011–20132014–20162017–2019Linear χ2 value
Women       
 AF patients, n25453694918803094  
 Age, median (IQR)62 (55–67)63 (56–69)63 (57–69)64 (58–70)65 (59–71)—<0.001
  Age ≥ 75, n (%)8 (3.1)35 (6.5)77 (8.1)239 (12.7)420 (13.6)52.2<0.001
  Age 65–74, n (%)90 (35.4)207 (38.6)334 (35.2)676(36.0)1254 (40.5)6.90.009
 Time in hospital (d; median, IQR)11 (8–13)9 (7–11)6 (4–8)5 (3–6)4 (3–5)—<0.001
 Hospital deaths, n (%)————2 (0.06%)—0.230
 Comorbidity, n (%)       
  Heart failure6 (2.4)7 (1.3)9 (0.9)44 (2.3)176 (5.7)52.1<0.001
  Hypertension121 (47.6)301 (56.2)540 (56.9)1077 (57.3)1860 (60.1)14.8<0.001
  Diabetes mellitus32 (12.6)83 (15.5)164 (17.3)267 (14.2)533 (17.2)2.80.09
  Stroke/TIA/TE7 (2.8)32 (6.0)55 (5.8)85 (4.5)236 (7.6)12.00.001
  Vascular disease20 (7.9)41 (7.6)80 (8.4)232 (12.3)464 (15.0)44.7<0.001
 CHA2DS2-VA score (mean ± SD)1.17 ± 1.061.43 ± 1.191.46 ± 1.261.56 ± 1.311.81 ± 1.39—<0.001
  Score 0, n (%)78 (30.7)128 (23.9)246 (25.9)479 (25.5)629 (20.3)21.3<0.001
  Score 1 n (%)91 (35.8)177 (33.0)286 (30.2)506 (26.9)751 (24.3)36.3<0.001
  Score ≥ 2 n (%)85 (33.5)231 (43.1)417 (43.9)895 (47.6)1714 (55.4)85.5<0.001
 CHADS2 score (mean ± SD)0.74 ± 0.740.89 ± 0.840.93 ± 0.880.95 ± 0.901.11 ± 0.97—<0.001
  Score 0, n (%)106 (41.7)191 (35.6)331 (34.9)653 (34.7)923 (30.0)23.7<0.001
  Score 1, n (%)112 (44.1)241 (45.0)420 (44.3)798 (42.4)1243 (40.2)7.60.006
  Score ≥ 2, n (%)36 (14.2)104 (19.4)198 (20.9)429 (22.8)928 (30.0)70.5<0.001
Men       
 AF patients, n6011121188138126087  
 Age, median (IQR)55 (47–65)57 (48–65)58 (50–65)59 (51–66)60 (52–66)—<0.001
  Age ≥ 75, n (%)33 (5.5)56 (5.0)104 (5.5)261 (6.8)403 (6.6)5.70.017
  Age 65–74, n (%)124 (20.6)247 (22.0)377 (20.0)826 (21.7)1554 (25.5)23.6<0.001
 Time in hospital (d; median, IQR)9 (7–12)8 (6–10)6 (4–7)4 (3–6)4 (3–5)—<0.001
 Hospital deaths, n (%)—1 (0.09%)——1 (0.02%)—0.529
 Comorbidity, n (%)       
  Heart failure6 (1.0)13 (1.2)14 (0.7)75 (2.0)237 (3.9)68.6<0.001
  Hypertension223 (37.1)513 (45.8)799 (42.5)1870 (49.1)3146 (51.7)73.8<0.001
  Diabetes mellitus54 (9.0)147 (13.1)238 (12.7)624 (16.4)1050 (17.2)46.4<0.001
  Stroke/TIA/TE18 (3.0)72 (6.4)148 (7.9)181 (4.7)447 (7.3)7.70.006
  Vascular disease37 (6.2)102 (9.1)169 (9.0)514 (13.5)992 (16.3)113.9<0.001
 CHA2DS2-VA score (mean ± SD)0.91 ± 1.081.14 ± 1.201.11 ± 1.191.25 ± 1.241.41 ± 1.30—<0.001
  Score 0, n (%)277 (46.1)421 (37.6)711(37.8)1280(33.6)1717(28.2)131.9<0.001
  Score 1, n (%)171 (28.5)347 (28.4)613 (32.6)1193(31.3)1940(31.9)4.40.035
  Score ≥ 2, n (%)153 (25.5)353 (28.9)557 (29.6)1339(35.1)2430(39.9)124.6<0.001
 CHADS2 score (mean ± SD)0.61 ± 0.780.78 ± 0.880.76 ± 0.910.84 ± 0.880.93 ± 0.93—<0.001
  Score 0, n (%)321 (53.4)506 (45.1)895 (47.6)1558 (40.9)2241 (36.8)111.8<0.001
  Score 1, n (%)218 (36.3)425 (37.9)670 (35.6)1519 (39.8)2512 (41.3)17.6<0.001
  Score ≥ 2, n (%)62 (10.3)190 (16.9)316 (16.8)735 (19.3)1334 (21.9)63.0<0.001