Insight on Efficacy of Renal Artery Denervation for Refractory Hypertension with Chronic Kidney Diseases: A Long-Term Follow-Up of 24-Hour Ambulatory Blood Pressure
Table 1
Subjects and baseline characteristics.
GFR 46–90 ml/min
GFR 15–45 ml/min
GFR <15 ml/min
value
N
21
19
14
Male (%)
9 (42.85)
7 (36.84)
5 (35.71)
0.89
Hypertension course (y)
3 (3,10)
20 (6,20)
13.75 (10,25)
0.56
Diabetes (%)
10 (47.62)
8 (42.11)
5 (35.71)
0.78
Heart failure (%)
4 (19.05)
5 (26.32)
6 (42.86)
0.30
ASCVD (%)
8 (38.10)
7 (36.84)
5 (35.71)
0.89
Age (y)
51.67 ± 10.73
52.58 ± 13.36
59.07 ± 12.14
0.18
Height (cm)
165.43 ± 9.98
166.53 ± 7.38
164.86 ± 8.76
0.86
Weight (kg)
73.33 ± 20.62
65.95 ± 12.61
62.00 ± 10.95
0.11
BMI (kg/cm2)
26.39 ± 4.64
23.34 ± 3.31
22.60 ± 3.17
0.01
HR (bpm)
75.38 ± 13.34
70.26 ± 12.03
71.14 ± 12.17
0.40
Scr (mg/dL)
1.10 ± 0.22
2.72 ± 0.88
9.71 ± 4.37
<0.01
eGFR (ml/min)
79.69 ± 30.18
31.35 ± 9.89
8.59 ± 4.24
<0.01
Hemoglobin (g/L)
133.71 ± 19.21
108.47 ± 18.98
93.14 ± 15.02
<0.01
Thrombocyte (×10^9/L)
222.48 ± 61.95
235.37 ± 107.67
205.36 ± 74.20
0.60
HbA1c (%)
6.35 ± 0.88
5.84 ± 0.71
5.38 ± 0.73
<0.01
Total bilirubin (mmol/L)
9.82 ± 4.22
7.86 ± 3.44
5.89 ± 2.80
<0.01
Albumin (g/L)
40.70 ± 6.45
35.99 ± 5.45
34.05 ± 5.46
<0.01
Potassium (mmol/L)
3.92 ± 0.40
4.17 ± 0.68
4.68 ± 0.84
<0.01
Sodium (mmol/L)
141.98 ± 2.97
140.79 ± 2.84
140.89 ± 4.94
0.51
Uric acid (mmol/L)
416.48 ± 125.37
460.61 ± 119.63
441.17 ± 95.54
0.49
Total cholesterol (mmol/L)
4.30 ± 1.16
3.71 ± 0.97
3.71 ± 0.57
0.10
Triglyceride (mmol/L)
2.02 ± 1.05
1.44 ± 0.80
1.06 ± 0.58
<0.01
LDL (mmol/L)
2.18 ± 1.25
1.75 ± 0.65
2.03 ± 0.70
0.35
HDL (mmol/L)
1.31 ± 0.77
1.38 ± 0.83
1.24 ± 0.44
0.87
LAD (cm)
4.27 ± 0.65
4.34 ± 0.41
4.72 ± 0.48
0.04
LVEDd (cm)
5.01 ± 0.62
5.40 ± 0.55
5.74 ± 0.28
<0.01
IVST (cm)
1.26 ± 0.29
1.28 ± 0.22
1.38 ± 0.24
0.39
LVEF (%)
63.95 ± 10.41
58.92 ± 8.91
62.04 ± 5.75
0.21
E/e
13.70 ± 5.57
15.05 ± 6.67
17.88 ± 6.88
0.17
Note. Data are mean ± SD, median with interquartile range, or n (%). BMI: body mass index; Scr: serum creatinine; eGFR: estimated glomerular filtration rate, male = ((140-age) × kg(/(Scr(mg/dL) 72), female = ((140-age) × kg × 0.85)/(Scr(mg/dL) × 72); HbA1c: glycosylated hemoglobin; Scr: serum creatinine; eGFR: estimated glomerular filtration rate hemoglobin(eGFR); LDL: low-density lipoprotein cholesterol; HDL: high-density lipoprotein cholesterol; LAD: left atrial diameter; LVEDd: left ventricular end diastolic diameter; IVST: interventricular septal thickness; LVEF: left ventricular ejection fraction; E/e: ratio of early diastolic mitral flow velocity to early diastolic mitral annulus tissue velocity; SBP: systolic blood pressure; DBP: diastolic blood pressure; ASCVD: atherosclerotic cardiovascular disease.
