| | Variables | Overall | LA/LAA thrombi (-) | LA/LAA thrombi (+) | P Value |
| | n | 1210 | 1071 | 139 | | | Age, years (mean ± SD) | 61.20 (10.08) | 60.80 (10.12) | 64.29 (9.29) | <0.001 | | Male, n (%) | 720 (59.5) | 645 (60.2) | 75 (54.0) | 0.185 | | BMI, kg/m2 (mean ± SD) | 26.75 (12.89) | 26.65 (11.76) | 27.53 (19.57) | 0.448 | | Smoke, n (%) | 231 (19.1) | 211 (19.7) | 20 (14.4) | 0.166 | | Alcohol, n (%) | 204 (16.9) | 180 (16.8) | 24 (17.3) | 0.987 | | Hypertension, n (%) | 683 (56.4) | 595 (55.6) | 88 (63.3) | 0.1 | | DM, n (%) | 204 (16.9) | 175 (16.3) | 29 (20.9) | 0.223 | | Myocardial infarction, n (%) | 30 (2.5) | 23 (2.1) | 7 (5.0) | 0.077 | | Previous HF, n (%) | 500 (41.3) | 398 (37.2) | 102 (73.4) | <0.001 | | Vascular disease, n (%) | 46 (3.8) | 39 (3.6) | 7 (5.0) | 0.567 | | Stroke/TIA, n (%) | 301 (24.9) | 257 (24.0) | 44 (31.7) | 0.063 | | Coronary heart disease, n (%) | 370 (30.6) | 320 (29.9) | 50 (36.0) | 0.171 | | Paroxysmal AF, n (%) | 698(57.7) | 686(64.1) | 12(8.6) | <0.001 | | Persistent AF, n (%) | 512 (42.3) | 385 (35.9) | 127 (91.4) | <0.001 | | CHA2DS2 score, (M [QL, QU]) | 1.00 [1.00, 3.00] | 1.00 [1.00, 3.00] | 2.00 [1.00, 3.00] | <0.001 | | CHA2DS2-VASc score, (M [QL, QU]) | 3.00 [1.00, 4.00] | 3.00 [1.00, 4.00] | 4.00 [2.00, 5.00] | <0.001 | | RDW, % (mean ± SD) | 42.41 (3.87) | 42.27 (3.90) | 43.52 (3.44) | <0.001 | | LDL-C, mmol/L (mean ± SD) | 2.52 (0.79) | 2.52 (0.79) | 2.52 (0.79) | 0.941 | | D-dimer, μg/L (M [QL, QU]) | 0.08 [0.05, 0.15] | 0.08 [0.05, 0.15] | 0.10 [0.06, 0.19] | 0.003 | | Fib, g/L (mean ± SD) | 2.91 (1.06) | 2.88 (1.05) | 3.18 (1.11) | 0.002 | | BNP, pg/mL (M [QL, QU]) | 87.45 [37.00, 202.75] | 73.30 [31.80, 178.50] | 251.00 [130.50, 413.50] | <0.001 | | Cr, mg/dL (mean ± SD) | 72.72 (21.16) | 72.21 (21.42) | 76.63 (18.72) | 0.021 | | Uric acid, μmol/L (mean ± SD) | 324.13 (93.21) | 321.02 (91.96) | 348.15 (99.47) | 0.001 | | E-wave, cm/s (mean ± SD) | 80.93 (32.31) | 78.67 (31.47) | 98.42 (33.44) | <0.001 | | e’ velocity, cm/s (mean ± SD) | 6.41 (2.01) | 6.45 (2.00) | 6.12 (2.02) | 0.073 | | E/e' ratio (mean ± SD) | 13.38 (5.31) | 12.88 (4.87) | 17.25 (6.78) | <0.001 | | LA diameter, mm (mean ± SD) | 37.90 (5.66) | 37.24 (5.35) | 42.99 (5.41) | <0.001 | | LVEDV, mL (mean ± SD) | 102.45 (26.83) | 101.78 (26.17) | 107.62 (31.08) | 0.016 | | LVESV, mL (mean ± SD) | 39.96 (15.73) | 39.03 (14.91) | 47.12 (19.64) | <0.001 | | LVEF, % (mean ± SD) | 61.44 (7.69) | 61.99 (7.26) | 57.17 (9.39) | <0.001 |
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Abbreviations: BMI, body mass index; DM, diabetes mellitus; HF, heart failure; RDW, red cell distribution width; LDL –C, low-density lipoprotein; BNP, B-type natriuretic peptide; Cr, creatinine; LA, left atrial; LVEDV, left ventricular end-diastolic volume; LVESV, left ventricular end-systolic volume; LVEF, Left ventricular ejection fraction.
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