Research Article
Assessment of Clinical Features in HIV-Infected Patients with Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention in China
Table 1
The demographic information, previous medical history, and laboratory results at admission compared between PLWH and HIV-negative controls.
| | | PLWH (n = 48) | HIV-negative controls (n = 48) | value |
| | Age (years, mean and SD) | 53.6 ± 10.6 | 53.0 ± 10.3 | 0.777 | | Male (n, %) | 46 (95.8%) | 46 (95.8%) | 1.000 | | Current smoker (n, %) | 27 (56.3%) | 32 (66.7%) | 0.294 | | BMI (kg/m2, mean and SD) | 24.7 ± 4.5 | 26.8 ± 3.8 | 0.018 | | Hypertension (n, %) | 18 (37.5%) | 31 (64.6%) | 0.008 | | BP (mean of systolic and diastolic BP (mmHg) ± SD) | 102 ± 13 | 104 ± 13 | 0.315 | | Diabetes mellitus (n, %) | 21 (43.8%) | 21 (43.8%) | 1.000 | | On insulin (n, %) | 6 (12.5%) | 5 (10.4%) | 0.749 | | Chronic kidney disease (n, %) | 2 (4.2%) | 4 (8.3%) | 0.677 | | Family history of CVD (n, %) | 12 (25%) | 20 (41.7%) | 0.083 |
| | Medications on admission (n, %) | | Aspirin | 14 (29.2%) | 9 (18.8%) | 0.232 | | Clopidogrel | 10 (20.8%) | 5 (10.4%) | 0.160 | | Statin | 23 (47.9%) | 5(10.4%) | <0.001 | | Β receptor blocker | 8 (16.7%) | 3 (6.3%) | 0.109 | | RAAS inhibitor | 11 (22.9%) | 14 (29.8%) | 0.447 |
| | CAD presentation (n, %) | | STEMI | 16 (33.3%) | 19 (39.5%) | 0.577 | | NSTEMI | 11 (22.9%) | 13 (27.0%) | | | UA | 21 (43.8%) | 16 (33.3%) | |
| | Echocardiographic parameters | | LVEF (%, mean and SD) | 52 ± 14 | 56 ± 9 | 0.069 | | LVDD (n, %) | 29 (60.4%) | 33 (71.7%) | 0.247 | | LVMI (g/m2, median and IQR) | 96 (77–114) | 88 (74–104) | 0.137 |
| | Baseline labs (mean and SD/median and IQR) | | Triglycerides (mmol/L) | 1.60 (1.05–2.25) | 1.55 (1.10–2.20) | 0.781 | | Total cholesterol (mmol/L) | 3.73 ± 1.34 | 4.37 ± 1.13 | 0.016 | | LDL-C (mmol/L) | 1.95 ± 0.77 | 2.69 ± 0.99 | <0.001 | | HDL-C (mmol/L) | 0.79 ± 0.22 | 0.92 ± 0.21 | 0.006 | | cTnI (ng/ml | 0.21 (0.09–0.92) | 0.21 (0.05–2.91) | 0.118 | | BNP (pg/ml) | 76 (39–386) | 140 (99–236) | 0.470 | | D-dimer (mg/L) | 0.28 (0.15–0.69) | 0.57 (0.43–0.93) | 0.089 | | Fasting blood-glucose (mmol/L) | 7.27 ± 2.76 | 8.87 ± 3.53 | 0.017 | | HbA1c (%) | 6.1 (5.5–6.7) | 5.9 (5.4–8.2) | 0.170 | | Creatinine (mmol/L) | 79 ± 30 | 78 ± 24 | 0.871 | | Leukocyte counts (109/L) | 5.64 ± 1.83 | 9.39 ± 3.61 | <0.001 | | Hemoglobin (g/dL) | 13.9 ± 5 | 14.5 ± 1.4 | 0.493 | | CRP (mg/dL) | 2.5 (1.2–7.2) | 5 (1.2–9.7) | 0.722 |
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PLWH: people living with HIV; BMI: body mass index; BP: blood pressure; CVD: cardiovascular disease; SD: standard deviation; IQR: interquartile range; RAAS: renin angiotensin aldosterone system; CAD: coronary artery disease; STEMI: ST-segment-elevation myocardial infarction; NSTEMI: non-ST-segment-elevation myocardial infarction; UA: unstable angina; LVEF: left ventricular ejection fraction; LVDD: left ventricular diastolic dysfunction; LVMI: left ventricular mass index; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; BNP: brain natriuretic peptide; HbA1c: hemoglobin A1c; CRP: C-reactive protein.
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