Research Article

Joint Analysis of Morphological Parameters and In Silico Haemodynamics of the Left Atrial Appendage for Thrombogenic Risk Assessment

Table 2

Volumetric and morphological features of patients with and without history of TIA/CVA.

CharacteristicsControl (n = 38)TIA/CVA (n = 33) value

Max. ostium diameter (mm)25.77 ± 4.4030.20 ± 4.90<0.001
Min. ostium diameter (mm)17.46 ± 3.6619.63 ± 2.950.01
Mean ostium diameter (mm)21.62 ± 3.7024.91 ± 3.660.001
Min. ostium radius (mm)6.99 ± 2.378.20 ± 1.810.02
Ostium area (mm2)367.18 ± 125.16486.35 ± 148.42<0.001
Ostium perimeter (mm)71.16 ± 12.2780.99 ± 12.140.001
Eccentricity0.32 ± 0.100.34 ± 0.080.24
LAA height (mm)14.80 (9.18–22.93)15.34 (8.83–30.63)0.25
Length of the centreline (mm)34.48 ± 7.0638.82 ± 8.740.05
Tortuosity of the centreline0.79 (0.50–0.96)0.77 (0.45–0.88)0.36
LAA anterior distance (mm)13.87 ± 3.7516.03 ± 3.180.01
LAA posterior distance (mm)11.38 ± 3.1712.83 ± 3.540.08
LAA anterior-posterior distance (mm)25.26 ± 6.7028.86 ± 6.380.02
Bending (degrees)114 ± 17.55103 ± 23.840.07
Atrium volume (ml)163 (82–256)164 (100–269)0.94
LAA area (mm2)2225 (1183–3918)2677 (1747–6006)0.03
LAA volume (ml)6.63 (2.59–15.50)8.09 (4.12–15.88)0.02
LAA shape
(i) Chicken-wing
(ii) Non-chicken-wing
6 (15.79%)
32 (84.21%)
4 (13.33%)
26 (86.67%)
0.53
0.45
LAA shape
(i) Chicken-wing6 (15.79%)4 (13.33%)0.53
(ii) Cauliflowers10 (26.32%)8 (26.67%)0.82
(iii) Cactus13 (34.21%)7 (23.33%)0.26
(iv) Windsock9 (23.68%)11 (36.67%)0.82

AP = anterior-posterior; CVA = cerebrovascular accident; Max = maximum; Min = minimum; TIA = transient ischemic attack. Data were unclear for 3 TIA/CVA cases. Results were presented as mean ± SD or median (min–max) or n (%).