Trans-myocardial Extraction of Endothelin-1 Correlates with Increased Microcirculatory Resistance following Percutaneous Coronary Intervention

Figure 2

(a) ET-1 extraction (Guide catheter–coronary sinus ET-1 in pg/ml) is proportional to increased upstream ET-1 in the guide catheter stationed in the aortic root both pre-PCI and post-PCI. (b) ET-1 TMG extraction (refers to post-PCI guide catheter CS ET-1 corrected for baseline TMG by subtracting pre-PCI guide catheter-CS ET-1) correlates with decreased hyperemic flow and increased Tmn. (c) Similarly with IMRc measured post-PCI. (d) ET-1 TMG extraction is significantly higher in the subgroup of patients with post-PCI IMRc ≥30.

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