Journal of Interventional Cardiology

Research Article

The Coronary Angiography-Derived Index of Microcirculatory Resistance Predicts Left Ventricular Performance Recovery in Patients with ST-Segment Elevation Myocardial Infarction

Table 1

Clinical, angiographic, and procedural characteristics.


Variable	Total (n = 80)

Demographics
Age (y)	58.0 ± 12.7
Male	64 (80.0%)
Body mass index (kg/m²)	24.7 ± 3.3
Cardiovascular risk factors
Hypertension	50 (62.5%)
Diabetes	26 (32.5%)
Hyperlipidemia	39 (48.8%)
Chronic kidney disease	4 (5.0%)
Current smoking	47 (58.8%)
Previous PCI	7 (8.8%)
Previous CABG	1 (1.3%)
Hemodynamic parameters
Systolic blood pressure (mmHg)	125.5 ± 19.4
Diastolic blood pressure (mmHg)	72.7 ± 10.4
Cardiac function (Killip class)
I	65 (81.3%)
II	8 (10.0%)
III	1 (1.3%)
IV	6 (7.5%)
Culprit vessel
Left anterior descending	51 (63.7%)
Left circumflex	8 (10.0%)
Right coronary artery	21 (26.3%)
Multivessel disease	61 (76.3%)
Symptom onset-to-balloon time (h)	7 (3.5–21.875)
Thrombus aspiration	7 (8.8%)
Glycoprotein IIb/IIIa inhibitor use	8 (10.0%)
Adjunctive balloon dilatation	5 (6.3%)
Total number of stents	1 (1-2)
Mean stent diameter (mm)	3.0 (2.75–3.5)
Total length of stents (mm)	32 (24–46)
Post-PCI TIMI flow grade
2	6 (7.5%)
3	74 (92.5%)
Coronary physiological measurements
cTFC	22.98 ± 13.00
caFFR	0.93 (0.89–0.94)
caIMR	43.2 ± 16.1
Laboratory profiles
Peak troponin I (ng/ml)	19742.35 (81.00–74380.48)
Peak CK-MB (ng/ml)	180.79 (56.02–238.48)
C-reactive protein (mg/L)	8.8 (1.0–30.3)
Low-density lipoprotein cholesterol (mmol/L)	2.88 ± 0.87
Estimated glomerular filtration rate (ml/min1.73 m²)	87.4 ± 20.6
Discharge medication
Aspirin	80 (100%)
P2Y₁₂ inhibitor	80 (100%)
Statins	80 (100%)
Beta-blocker	66 (82.5%)
ACEI/ARB	60 (75.0%)

PCI, percutaneous coronary intervention; CABG, coronary artery bypass graft; TIMI, thrombolysis in myocardial infarction; cTFC, corrected thrombolysis in myocardial infarction frame count; caFFR, coronary angiography-derived fractional flow reserve; caIMR, coronary angiography-derived index of microcirculatory resistance; ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker.