The Coronary Angiography-Derived Index of Microcirculatory Resistance Predicts Left Ventricular Performance Recovery in Patients with ST-Segment Elevation Myocardial Infarction
Table 5
Clinical variables and echocardiographic parameters of patients according to the optimal cutoff value for the predictive model.
Variable
The score < 2.33 (n = 29)
The score ≥ 2.33 (n = 51)
value
Age (y)
60.3 ± 15.6
56.7 ± 10.7
0.274
Body mass index (kg/m2)
24.4 ± 3.9
24.9 ± 2.9
0.453
Hypertension
15 (51.7%)
35 (68.6%)
0.133
Diabetes
7 (24.1%)
19 (37.3%)
0.229
Hyperlipidemia
12 (41.4%)
27 (52.9%)
0.320
Current smoking
16 (55.2%)
31 (60.8%)
0.624
Systolic blood pressure (mmHg)
125.1 ± 19.6
125.8 ± 19.5
0.888
Diastolic blood pressure (mmHg)
69.8 ± 11.0
74.4 ± 9.8
0.058
Multivessel disease
18 (62.1%)
43 (84.3%)
0.025
Symptom onset-to-balloon time (h)
8.0 (4.5–24.5)
6.0 (3.5–16.2)
0.312
Thrombus aspiration
0 (0.0%)
7 (13.7%)
0.094
Glycoprotein IIb/IIIa inhibitor use
2 (6.9%)
6 (11.8%)
0.756
Post-PCI TIMI flow grade 3
27 (93.1%)
47 (92.2%)
0.877
cTFC
17.6 ± 9.0
26.0 ± 14.0
0.002
caFFR
0.905 (0.83–0.925)
0.93 (0.91–0.945)
0.001
Peak troponin I (ng/ml)
9313.0 (40.9–54053.55)
25682.9 (82.0–91652.2)
0.091
Peak CK-MB (ng/ml)
80.9 (31.36–226.65)
194.0 (104.3–243.4)
0.039
Beta-blocker
23 (79.3%)
43 (84.3%)
0.571
ACEI/ARB
23 (79.3%)
37 (72.5%)
0.502
Change in LVEF
5.5 ± 6.6
−2.5 ± 6.6
<0.001
Change in WMSI
−0.05 (−0.25–0)
−0.16 (−0.47–−0.03)
0.165
Change in GLS
−2.4 ± 3.4
−1.8 ± 3.8
0.610
TIMI, thrombolysis in myocardial infarction; cTFC, corrected thrombolysis in myocardial infarction frame count; caFFR, coronary angiography-derived fractional flow reserve; caIMR, coronary angiography-derived index of microcirculatory resistance; ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker; LVEF, left ventricular ejection fraction; WMSI, wall motion score index; GLS, global longitudinal strain.