Characteristics and Pattern of Calcified Nodule and/or Nodular Calcification Detected by Intravascular Ultrasound on the Device-Oriented Composite Endpoint (DoCE) in Patients with Heavily Calcified Lesions Who Underwent Rotational Atherectomy-Assisted Percutaneous Coronary Intervention
Table 1
Baseline characteristics of all patients and comparison between those with and without calcified nodule.
Characteristics
All patients (N = 200)
CN (n = 87)
Non-CN (n = 113)
Age (years)
72.5 ± 9.4
72.7 ± 10.1
72.4 ± 8.8
0.832
Male gender
106 (53.0%)
48 (55.2%)
58 (51.3%)
0.589
Diabetes mellitus
113 (56.5%)
53 (60.9%)
60 (53.1%)
0.269
Hypertension
193 (96.5%)
87 (100.0%)
106 (93.8%)
0.019
Dyslipidemia
150 (75.0%)
64 (73.6%)
86 (76.1%)
0.681
Chronic kidney disease
87 (43.5%)
36 (41.4%)
51 (45.1%)
0.596
Hemodialysis
20 (10.0%)
6 (6.9%)
14 (12.4%)
0.199
Prior MI
43 (21.5%)
17 (19.5%)
26 (23.0%)
0.554
Prior PCI
17 (8.5%)
7 (8.0%)
10 (8.8%)
0.840
Prior CABG
16 (8.0%)
7 (8.0%)
9 (8.0%)
0.983
Current smoker
9 (4.5%)
5 (5.7%)
4 (3.5%)
0.506
LVEF (%)
61 (46, 69)
62 (47, 70)
61 (46, 67)
0.592
LVEF <30%
8 (4.3%)
3 (3.7%)
5 (4.7%)
1.000
Atrial fibrillation
25 (12.5%)
10 (11.5%)
15 (13.3%)
0.706
Clinical presentation
CCS
154 (77.0%)
64 (73.6%)
90 (79.6%)
0.311
ACS
46 (23.0%)
23 (26.4%)
23 (20.4%)
Medication at discharge
Aspirin
199 (99.5%)
87 (100.0%)
112 (99.1%)
1.000
P2Y12 inhibitors
Clopidogrel
166 (83.0%)
74 (85.1%)
92 (81.4%)
Ticagrelor
29 (14.5%)
11 (12.6%)
18 (15.9%)
0.563
Prasugrel
4 (2.0%)
1 (1.1%)
3 (2.7%)
Oral anticoagulant
19 (9.5%)
7 (8.0%)
12 (10.6%)
0.538
Statin
195 (97.5%)
84 (96.6%)
111 (98.2%)
0.655
Data presented as frequency and percentage, mean ± standard deviation, or median and interquartile range. A value<0.05 indicates statistical significance. CN, calcified nodule; MI, myocardial infarction; PCI, percutaneous coronary intervention; CABG, coronary artery bypass graft; LVEF, left ventricular ejection fraction; CCS, chronic coronary syndrome; and ACS, acute coronary syndrome.
