Research Article

Characteristics and Pattern of Calcified Nodule and/or Nodular Calcification Detected by Intravascular Ultrasound on the Device-Oriented Composite Endpoint (DoCE) in Patients with Heavily Calcified Lesions Who Underwent Rotational Atherectomy-Assisted Percutaneous Coronary Intervention

Table 2

Lesion and procedure characteristics of all patients and comparison between those with and without calcified nodule.

CharacteristicsAll patients (N = 200)CN (n = 87)Non-CN (n = 113)

Target vessel
 Left main8 (4.0%)4 (4.6%)4 (3.5%)
 Left anterior descending145 (72.5%)60 (69.0%)85 (75.2%)0.606
 Left circumflex8 (4.0%)5 (5.7%)3 (2.7%)
 Right coronary artery39 (19.5%)18 (20.7%)21 (18.6%)
Number of vessel disease
 145 (22.5%)16 (18.4%)29 (25.7%)
 278 (39.0%)34 (39.1%)44 (38.9%)0.602
 368 (34.0%)33 (37.9%)35 (31.0%)
 Left main9 (4.5%)4 (4.6%)5 (4.4%)
Lesion location
 Ostial11 (5.5%)7 (8.0%)4 (3.5%)0.215
 Proximal121 (60.5%)50 (57.5%)71 (62.8%)0.442
 Mid105 (52.5%)43 (49.4%)62 (54.9%)0.445
 Distal12 (6.0%)6 (6.9%)6 (5.3%)0.639
Angiographic moderate to severe calcification195 (97.5%)86 (98.9%)109 (96.5%)0.390
 Moderate40 (20.0%)17 (19.5%)23 (20.4%)0.583
 Severe155 (77.5%)69 (79.3%)86 (76.1%)
Chronic total occlusion lesion10 (5.0%)3 (3.4%)7 (6.2%)0.518
Ostial lesion61 (30.5%)28 (32.2%)33 (29.2%)0.650
Bifurcation64 (32.0%)28 (32.2%)36 (31.9%)0.961
Stent type
 Bare metal stent5 (2.5%)3 (3.5%)2 (1.8%)0.654
 Drug-eluting stent193 (97.5%)83 (96.5%)110 (98.2%)
Number of stents
 196 (48.5%)42 (48.8%)54 (48.2%)0.931
 >1102 (51.5%)44 (51.2%)58 (51.8%)
Max stent diameter3.0 (3.0, 3.5)3.5 (3.0, 3.5)3.0 (2.8, 3.5)0.292
Stent length38.0 (28.0, 52.0)36.5 (28.0, 52.0)38.0 (29.0, 52.0)0.733
Cutting or scoring balloon17 (8.5%)5 (5.7%)12 (10.6%)0.221
Max balloon3.3 (3.0, 3.5)3.0 (2.8, 3.6)3.3 (3.0, 3.5)0.970
Rotational atherectomy
 Final burr1.5 (1.5, 1.8)1.5 (1.5, 1.8)1.5 (1.5, 1.8)0.217
 Burr-to-artery ratio0.49 ± 0.090.49 ± 0.100.49 ± 0.090.740
 >1 burr47 (23.5%)19 (21.8%)28 (24.8%)0.627
Perioperative complications10 (5.0%)8 (9.2%)2 (1.8%)0.022
 Dissection and acute closure4 (2.0%)2 (2.3%)2 (1.8%)1.000
 Perforation0 (0.0%)0 (0.0%)0 (0.0%)
 Slow flow or IABP2 (1.0%)2 (2.3%)0 (0.0%)0.188
 Myocardial infarction6 (3%)6 (6.9%)0 (0%)0.006
 Cardiac tamponade0 (0%)0 (0%)0 (0%)
 Cerebral infarction1 (0.5%)1 (1.1%)0 (0%)0.437

Data presented as frequency and percentage, mean ± standard deviation, or median and interquartile range. A value<0.05 indicates statistical significance. Abbreviations: CN, calcified nodule.