Research Article

Characteristics and Pattern of Calcified Nodule and/or Nodular Calcification Detected by Intravascular Ultrasound on the Device-Oriented Composite Endpoint (DoCE) in Patients with Heavily Calcified Lesions Who Underwent Rotational Atherectomy-Assisted Percutaneous Coronary Intervention

Table 3

Angiographic findings and intravascular ultrasound findings compared between the patients with and without calcified nodule.

All patients (N = 200)CN (n = 87)Non-CN (n = 113)

Angiographic findings
 Preintervention
  Lesion length (mm)37.36 ± 17.0935.49 ± 17.2338.76 ± 16.930.196
  Reference lumen diameter (mm)2.61 ± 0.582.65 ± 0.642.58 ± 0.530.388
  Minimum lumen diameter (mm)0.48 ± 0.330.50 ± 0.370.47 ± 0.300.473
  Diameter stenosis (%)81.35 ± 12.5681.13 ± 12.5181.52 ± 12.660.830
 Postintervention
  Reference lumen diameter (mm)2.73 ± 0.452.78 ± 0.452.69 ± 0.450.144
  Minimum lumen diameter (mm)2.43 ± 0.402.46 ± 0.422.41 ± 0.380.407
  Diameter stenosis (%)10.68 ± 7.2111.52 ± 7.8310.04 ± 6.670.152
  Acute lumen gain (mm)1.95 ± 0.451.95 ± 0.421.94 ± 0.470.843

IVUS parametern = 125n = 54n = 71
 Mean reference vessel3.28 ± 0.703.35 ± 0.743.24 ± 0.670.281
 Minimal stent area6.56 ± 2.356.67 ± 2.586.48 ± 2.170.648
  Minimal stent area ≤5 mm232 (25.6%)14 (25.9%)18 (25.4%)0.942
  Minimal stent area ≤5.5 mm243 (34.4%)19 (35.2%)24 (33.8%)0.872
 Asymmetrical stent expansion6 (4.8%)5 (9.3%)1 (1.4%)0.084

IVUS findings: plaque characteristics
 Superficial calcification196 (98.0%)87 (100.0%)109 (96.5%)0.134
 Concentric calcification182 (91.0%)80 (92.0%)102 (90.3%)0.679
 Napkin ring sign100 (50.0%)43 (49.4%)57 (50.4%)0.887
 Reverberation140 (70.0%)53 (60.9%)87 (77.0%)0.014
 Calcium fracture164 (82.0%)75 (86.2%)89 (78.8%)0.174

Data presented as frequency and percentage or mean ± standard deviation. A value<0.05 indicates statistical significance. IVUS data OptiCross™ that transferred to storage source can be reviewed, but it cannot be offline analysis for measurement information. At the other site of the calcified nodule. CN, calcified nodule; IVUS, intravascular ultrasound.