The “L-Sandwich” Strategy for True Coronary Bifurcation Lesions: A Randomized Clinical Trial

Table 2

Lesion and procedural characteristics at pre- and post-PCI.

		“L-sandwich” (n = 38)	Two-stent (n = 32)	Single-stent + DCB (n = 29)
Lesion location (n)
LM-LCX		8	13	6	0.579
LAD-D		17	11	13
LCX-OM		10	5	7
RCA-PLA/PDA		3	3	3
Bifurcation angle (degrees)		62.58 ± 17.15	56.78 ± 12.90	55.83 ± 10.97	0.106
Main vessel
Reference diameter (mm)		3.37 ± 0.41	3.36 ± 0.19	3.43 ± 0.35	0.652
Target lesion length (mm)		22.56 ± 6.25	20.81 ± 6.43	20.79 ± 7.6	0.452
Stent length (mm)		26.05 ± 6.33	25.83 ± 6.21	25.69 ± 7.76	0.866
MLD (mm)	Pre-PCI	0.91 ± 0.22	0.89 ± 0.26	0.95 ± 0.23	0.533
	Post-PCI	3.31 ± 0.41	3.29 ± 0.19	3.37 ± 0.36	0.594
Acute gain (mm)		2.39 ± 0.33	2.40 ± 0.34	2.42 ± 0.33	0.944
Residual stenosis (%)		1.83 ± 1.90	2.11 ± 1.93	1.78 ± 1.64	0.730
Side branch
Reference diameter (mm)		2.97 ± 0.13	2.92 ± 0.14	2.92 ± 0.11	0.207
Target lesion length (mm)		28.67 ± 3.32	29.59 ± 3.72	28.80 ± 4.45	0.572
Cutting balloon [n, %]		38(100)	2(6.3)	29(100)	<0.001
Stent length (mm)		24.40 ± 3.61	34.13 ± 2.85		<0.001
DCB length (mm)		15.00 ± 0.00		32.37 ± 3.82	<0.001
Ostium MLD (mm)	Pre-PCI	0.65 ± 0.09	0.70 ± 0.09	0.66 ± 0.11	0.113
	Post-PCI	2.42 ± 0.14	2.77 ± 0.15	2.24 ± 0.16	<0.001
					^†<0.001
					^‡<0.001
Ostium acute gain (mm)		1.76 ± 0.14	2.07 ± 0.12	1.57 ± 0.21	<0.001
					^†<0.001
					^‡<0.001
Ostium residual stenosis (%)		18.50 ± 4.50	5.01 ± 1.53	23.44 ± 5.34	<0.001
					^†<0.001
					^‡<0.001
Shaft MLD (mm)	Pre-PCI	0.74 ± 0.08	0.77 ± 0.10	0.73 ± 0.13	0.272
	Post-PCI	2.73 ± 0.13	2.70 ± 0.14	2.27 ± 0.15	0.908
					^†<0.001
					^‡<0.001
Shaft acute gain(mm)		2.00 ± 0.10	1.93 ± 0.12	1.53 ± 0.18	0.117
					^†<0.001
					^‡<0.001
Shaft residual stenosis (%)		7.87 ± 1.38	7.50 ± 1.65	22.4 ± 5.11	1.000
					^†<0.001
					^‡<0.001
POT [n (%)]		36 (94.7)	32 (100)	27 (93.1)	0.349
Procedural time (min)		79.29 ± 11.83	105.72 ± 11.64	64.69 ± 11.88	<0.001
					^†<0.001
					^‡<0.001
Contrast volume (ml)		59.37 ± 9.54	90.25 ± 19.11	50.69 ± 10.81	<0.001
					^†<0.001
					^‡0.035

: “L-sandwich” strategy vs. two-stent strategy; ^†: two-stent strategy vs. single-stent + DCB strategy, ^‡: “L-sandwich” strategy vs. single-stent + DCB strategy, bonferroni’s post hoc test. D: diagonal artery; DCB: drug-coated balloon; LAD: left anterior descending coronary; LCX: left circumflex coronary artery; MLD: minimum lumen diameter; OM: obtuse marginal artery; PDA: posterior descending branch; PLA: posterior of left ventricle artery; RCA: right coronary artery; PCI: percutaneous coronary intervention; POT: proximal optimization technique.