Review Article
Lower Plasma miR-223 Level Is Associated with Clopidogrel Resistance in Acute Coronary Syndrome: A Systematic Review and Meta-Analysis
Table 1
Characteristics of the studies included.
| | Study | Region | Recruitment time | Study type | Disease type | Sample size | Experimental sample | Analysis method | Platelet function test | miRNA detection method | Quality score |
| | Shi et al. 2013 | China | NS | Cohort study | NSTE-ACS | 33 | Plasma | Univariate/multivariate analysis | LTA | qRT-PCR | 8 | | Li et al. 2017 | China | 2013-2014 | Cohort study | NSTE-ACS | 39 | Plasma | Univariate/multivariate analysis | LTA | qRT-PCR | 8 | | Guo et al. 2020 | China | 2017-2018 | Cohort study | CHD | 119 | Plasma | Univariate/multivariate analysis | TEG | qRT-PCR | 7 | | Zhang et al. 2021 | China | 2016-2017 | Cohort study | NSTE-ACS | 208 | Plasma | Univariate/multivariate analysis | Flow cytometer | qRT-PCR | 9 |
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NS: not sure; NSTE-ACS: non-st-segment elevation acute coronary syndrome; LTA: light transmittance aggregometry; TEG: thrombelastograph coagulation analyzer; CHD: coronary heart disease.
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