Protective Effects of Simvastatin, a Lipid Lowering Agent, against Oxidative Damage in Experimental Diabetic Rats

<table>Effect of simvastatin (SMV) and glibenclamide treatment on (a) plasma glutathione and (b) vitamin C in normal and streptozotocin-induced diabetic rats. Data are expressed as means ± SEM (<svg height="11.125" id="M25" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 11.125" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>). *Significantly different from control group (<svg height="11.375" id="M26" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>). <sup>#</sup>Significantly different from diabetic-untreated group (<svg height="11.375" id="M27" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg>).</table>

Journal of Lipids

fig3

Figure 3

Figure 3: Protective Effects of Simvastatin, a Lipid Lowering Agent, against Oxidative Damage in Experimental Diabetic Rats 