Research Article
Genetic Association between Lipid-Regulating Drug Targets and Diabetic Retinopathy: A Drug Target Mendelian Randomization Study
Table 2
The results of pleiotropy test.
| | Exposure | Intercept in MR-Egger regression | RSSobs in MR-PRESSO global test | | Value | value | Value | value |
| | LDL-C targets | | | | | | HMGCR | — | — | — | — | | PCSK9 | 0.010891 | 0.602 | 11.455660 | 0.505 | | NPC1L1 | — | — | — | — | | HDL-C targets | | | | | | CETP | -0.015321 | 0.268 | 36.964580 | 0.968 | | SCARB1 | -0.068692 | 0.026 | 19.968930 | 0.388 | | PPARG | 0.133891 | 0.065 | 14.509800 | 0.073 | | TG targets | | | | | | PPARA | — | — | — | — | | LPL | -0.038611 | 0.227 | 19.424070 | 0.153 |
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