Branched RNA: A New Architecture for RNA Interference
Figure 6
Inhibitory capacity of branched anti-TNF-α siRNAs. The inhibitory capacity of the siRNA duplexes are expressed as double strand concentration for comparative purposes. A 100-nM double strand concentration is equivalent to a concentration of 100 nM of unmodified siRNA duplex, 50 nM of siRNA 1, and 2 and 25 nM of siRNA 3. Transfection of siRNAs was carried out using oligofectamine. Values are represented as the average ±ES, and are compared to a scrambled sequence. , ANOVA Test, Bonferroni post-test.
