The Effects of Molecular Crowding on the Structure and Stability of G-Quadruplexes with an Abasic Site

Figure 1

(a) Structure of human telomere (5′-A(G₃T₂A)₃G₃-3′) G-quadruplex in the presence of Na⁺ (PDB ID: 143D). (b) Schematic illustration of G-quadruplex AP-0 with a top G-quartet plane (green), middle G-quartet plane (purple), and bottom G-quartet plane (red). The numbers indicate the position of abasic sites (AP-𝑋 (𝑋 indicates 1 to 11)).

(a)

(b)