Research Article
Genetic Predisposition for Dermal Problems in Hexavalent Chromium Exposed Population
Table 5
Influence of various covariates and genotypes on dermatological adversities among symptomatic exposed compared with asymptomatic exposed group.
| | Characters | Category | Exposed SYMP | Exposed ASYMP | OR (95% CI) | | () (%) | () (%) |
| | Sex | Males | 20 (52.6) | 59 (54.6) | 1 | | Females | 18 (47.4) | 49 (45.4) | 1.08 (0.517–2.273) |
| | Age (years) | ≤35 | 20 (52.6) | 61 (56.5) | 1 | | >35 | 18 (47.4) | 47 (43.5) | 1.17 (0.556–2.453 |
| | Smoking | Never | 30 (79) | 88 (81.5) | 1 | | Current/past | 8 (21) | 20 (18.5) | 1.17 (0.468–2.94) |
| | Duration of | ≤20 | 19 (50) | 62 (57.4) | 1 | | residence (years) | >20 | 19 (50) | 46 (42.6) | 1.35 (0.642–2.83) |
| | GSTT1 | Wild | 27 (71) | 85 (78.7) | 1 | | Null | 11 (29) | 23 (21.3) | 1.51 (0.651–3.484) |
| | GSTM1 | Wild | 24 (63.2) | 87 (80.6) | 1 | | Null | 14 (36.8) | 21 (19.4) | 2.42 (1.071–5.451)* |
| | NQO1 | Wild (C/C) | 16 (44.4) | 38 (36.2) | 1 | | Mutant (C/T + T/T) | 20 (55.6) | 67 (63.8) | 0.71 (0.329–1.529) |
| | hOGG1 | Wild (C/C) | 13 (34.2) | 56 (51.8) | 1 | | Mutant (C/G + G/G) | 25 (65.8) | 52 (48.2) | 2.07 (0.96–4.469) |
|
|
SYMP: symptomatic, ASYMP: asymptomatic, OR: odds ratio, CI: confidence interval; *.
|
