Exposure to a Pathological Condition May Be Required for the Cells to Secrete Exosomes Containing mtDNA Aberration

Figure 1

Typical gel images of exosomal mtDNA PCR products using primer sets described in Table 1. (a) NSC and GBM in the figure represent the mtDNA PCR products using exosomes isolated from neural stem cells (NSC) and glioblastoma multiforme (GBM) cell culture media as the sample. (b) iPS-NSC and iPS-NSC-AD in the figure represent the mtDNA PCR products using exosomes isolated from NSCs derived from iPS cells reprogrammed from B lymphocytes of control (iPS-NSC) and AD (iPS-NSC-AD) subjects.

(a)

(b)