Research Article

Synthesis and Evaluation of MGB Polyamide-Oligonucleotide Conjugates as Gene Expression Control Compounds

Scheme 1

Synthesis of pyrrole polyamides. Reagents and conditions: i EDCI, DMAP, CH2Cl2, rt, 6 (80%). Compounds 2, 3, 4, and 5 were prepared as previously described [10ā€“13].